Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
Nitric oxide/nitric oxide synthase system in the pathogenesis of neurodegenerative disorders—an overview
OM Iova, GE Marin, I Lazar, I Stanescu, G Dogaru… - Antioxidants, 2023 - mdpi.com
Nitric oxide, a ubiquitous molecule found throughout the natural world, is a key molecule
implicated in many central and benefic molecular pathways and has a well-established role …
implicated in many central and benefic molecular pathways and has a well-established role …
LRRK2 Kinase Inhibition Attenuates Neuroinflammation and Cytotoxicity in Animal Models of Alzheimer's and Parkinson's Disease-Related Neuroinflammation
V Mutti, G Carini, A Filippini, S Castrezzati, L Giugno… - Cells, 2023 - mdpi.com
Chronic neuroinflammation plays a crucial role in the progression of several
neurodegenerative diseases (NDDs), including Parkinson's disease (PD) and Alzheimer's …
neurodegenerative diseases (NDDs), including Parkinson's disease (PD) and Alzheimer's …
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders
Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …
Identifying treatment targets is challenging because the diseases are resulting from …
The potential therapeutic effect of phosphodiesterase 5 inhibitors in the acute ischemic stroke (AIS)
R AlRuwaili, HM Al-Kuraishy, M Alruwaili… - Molecular and Cellular …, 2023 - Springer
Acute ischemic stroke (AIS) is a focal neurological disorder that accounts for 85% of all
stroke types, due to occlusion of cerebral arteries by thrombosis and emboli. AIS is also …
stroke types, due to occlusion of cerebral arteries by thrombosis and emboli. AIS is also …
Role of NLRP3 inflammasome-mediated neuronal pyroptosis and neuroinflammation in neurodegenerative diseases
YH Han, XD Liu, MH Jin, HN Sun, T Kwon - Inflammation Research, 2023 - Springer
Background Neurodegenerative diseases are a common group of neurological disorders
characterized by progressive loss of neuronal structure and function leading to cognitive …
characterized by progressive loss of neuronal structure and function leading to cognitive …
A high-selectivity NIR fluorescent probe for detection of nitric oxide in saliva samples and living cells imaging
S Jiao, S Yang, Y Wang, A Ma - Sensors and Actuators B: Chemical, 2023 - Elsevier
In this study, a near-infrared Changsha dye (CS)-based fluorescent probe CS-Se for nitric
oxide (NO) detection was designed and synthesized. The reaction between CS-Se and NO …
oxide (NO) detection was designed and synthesized. The reaction between CS-Se and NO …
Resveratrol activates antioxidant protective mechanisms in cellular models of Alzheimer's disease inflammation
C Bartra, Y Yuan, K Vuraić, H Valdés-Quiroz… - Antioxidants, 2024 - mdpi.com
Resveratrol is a natural phenolic compound with known benefits against
neurodegeneration. We analyzed in vitro the protective mechanisms of resveratrol against …
neurodegeneration. We analyzed in vitro the protective mechanisms of resveratrol against …
Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS‐Induced Neuroinflammation by Interfering in the TLR4/NF‐κB‐MAPK Signaling Pathway …
JAC de Sousa, FVCS Azul, AB de Araújo… - Oxidative Medicine …, 2023 - Wiley Online Library
Neuroinflammation is present in the pathophysiological mechanisms of several diseases
that affect the central nervous system (CNS). Microglia have a prominent role in initiating …
that affect the central nervous system (CNS). Microglia have a prominent role in initiating …
Disease-modifying effects of a glial-targeted inducible nitric oxide synthase inhibitor (1400W) in mixed-sex cohorts of a rat soman (GD) model of epilepsy
Background Acute exposure to seizurogenic organophosphate (OP) nerve agents (OPNA)
such as diisopropylfluorophosphate (DFP) or soman (GD), at high concentrations, induce …
such as diisopropylfluorophosphate (DFP) or soman (GD), at high concentrations, induce …