Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China

Y Shang, C Pan, X Yang, M Zhong, X Shang… - Annals of intensive …, 2020 - Springer
Background The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all
over the world, posing a great pressure on critical care resources due to large number of …

Ventilator-induced lung injury

JR Beitler, A Malhotra… - Clinics in chest …, 2016 - chestmed.theclinics.com
As with most medical and pharmacologic interventions, mechanical ventilation must be
titrated within a therapeutic window, providing the required lifesustaining support while …

Ventilator-related causes of lung injury: the mechanical power

L Gattinoni, T Tonetti, M Cressoni, P Cadringher… - Intensive care …, 2016 - Springer
Purpose We hypothesized that the ventilator-related causes of lung injury may be unified in
a single variable: the mechanical power. We assessed whether the mechanical power …

Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Evolution of mortality over time in patients receiving mechanical ventilation

A Esteban, F Frutos-Vivar, A Muriel… - American journal of …, 2013 - atsjournals.org
Rationale: Baseline characteristics and management have changed over time in patients
requiring mechanical ventilation; however, the impact of these changes on patient outcomes …

The" baby lung" became an adult

L Gattinoni, JJ Marini, A Pesenti, M Quintel… - Intensive care …, 2016 - Springer
The baby lung was originally defined as the fraction of lung parenchyma that, in acute
respiratory distress syndrome (ARDS), still maintains normal inflation. Its size obviously …

Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU: cardiovascular, endocrine, hematologic, pulmonary, and renal …

R Nanchal, R Subramanian, CJ Karvellas… - Critical care …, 2020 - journals.lww.com
Objectives: To develop evidence-based recommendations for clinicians caring for adults
with acute or acute on chronic liver failure in the ICU. Design: The guideline panel …

Ventilator-induced lung injury: lessons from experimental studies

D Dreyfuss, G Saumon - American journal of respiratory and critical …, 1998 - atsjournals.org
Mechanical ventilation has been used to support acutely ill patients for several decades. But
clinicians are aware that, despite the life-saving potential of this assistance, it has several …

Acute respiratory distress syndrome

NJ Meyer, L Gattinoni, CS Calfee - The Lancet, 2021 - thelancet.com
Acute respiratory distress syndrome (ARDS) is an acute respiratory illness characterised by
bilateral chest radiographical opacities with severe hypoxaemia due to non-cardiogenic …

The concept of “baby lung”

L Gattinoni, A Pesenti - Applied Physiology in Intensive Care Medicine 1 …, 2012 - Springer
Background: The “baby lung” concept originated as an offspring of computed tomography
examinations which showed in most patients with acute lung injury/acute respiratory distress …