Significance: Mitochondrial (mt) reticulum network in the cell possesses amazing
ultramorphology of parallel lamellar cristae, formed by the invaginated inner mitochondrial …

Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …

Numerous reactive oxygen species (ROS) entities exist, and hydrogen peroxide (H2O2) is
very key among them as it is well known to possess a stable but poor reactivity capable of …

Superoxide/hydrogen peroxide production by site IQ in complex I of the electron transport
chain is conventionally assayed during reverse electron transport (RET) from ubiquinol to …

Diabetic kidney disease (DKD) is a common and severe complication of diabetes mellitus. If
left untreated, DKD can advance to end stage renal disease that requires either dialysis or …

Mitochondria are the powerhouses of the cell. They produce a significant amount of the
energy we need to grow, survive and reproduce. The same system that generates energy in …

Significance: Reactive oxygen species (ROS) are well known to promote innate immune
responses during and in the absence of microbial infections. However, excessive or …

Compartmentalisation of eukaryotic cells enables fundamental otherwise often incompatible
cellular processes. Establishment and maintenance of distinct compartments in the cell …

In the past, mitochondrial reactive oxygen species (mtROS) were considered a byproduct of
cellular metabolism. Due to the capacity of mtROS to cause oxidative damage, they were …

Previously studies found that Rheum palmatum L. water extract residues contains the
abundant five anthraquinones, and could be used as a renewable source to enrich active …