Nitric oxide (NO) is one of the critical components of the vasculature, regulating key
signaling pathways in health. In macrovessels, NO functions to suppress cell inflammation …

Although the pathobiology of atherosclerosis is a complex multifactorial process, blood flow-
induced shear stress has emerged as an essential feature of atherogenesis. This fluid drag …

The endothelial nitric oxide synthase (eNOS), the expression of which is regulated by a
range of transcriptional and posttranscriptional mechanisms, generates nitric oxide (NO) in …

Nitric oxide production in response to flow-dependent shear forces applied on the surface of
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …

A recombinant vaccine containing Aventis Pasteur's canarypox vector (ALVAC)–HIV and
gp120 alum decreased the risk of HIV acquisition in the RV144 vaccine trial. The substitution …

The endothelium, although only a single layer of cells lining the vascular and lymphatic
systems, contributes in multiple ways to vascular homeostasis. Subsequent to the 1980 …

▪ Abstract Endothelial nitric oxide synthase (eNOS) is expressed in vascular endothelium,
airway epithelium, and certain other cell types where it generates the key signaling molecule …

Catalyzed by endothelial nitric oxide (NO) synthase (eNOS) activity, NO is a gaseous
signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO …

The vascular endothelium synthesises the vasodilator and anti-aggregatory mediator nitric
oxide (NO) from L-arginine. This action is catalysed by the action of NO synthases, of which …

The complex regulation of eNOS (endothelial nitric oxide synthase) in cardiovascular
physiology occurs at multiple stages. eNOS mRNA levels are controlled both at the …