Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Relationship between quorum sensing and secretion systems

RT Pena, L Blasco, A Ambroa… - Frontiers in …, 2019 - frontiersin.org
Quorum sensing (QS) is a communication mechanism between bacteria that allows specific
processes to be controlled, such as biofilm formation, virulence factor expression, production …

The multiple signaling systems regulating virulence in Pseudomonas aeruginosa

P Nadal Jimenez, G Koch, JA Thompson… - Microbiology and …, 2012 - Am Soc Microbiol
Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Protein secretion systems in Pseudomonas aeruginosa: a wealth of pathogenic weapons

S Bleves, V Viarre, R Salacha, GPF Michel… - International Journal of …, 2010 - Elsevier
Pathogenic microorganisms have to face hostile environments while colonizing and
infecting their hosts. Unfortunately, they can cope with it and have evolved a number of …

Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

ME Skindersoe, M Alhede, R Phipps… - Antimicrobial agents …, 2008 - Am Soc Microbiol
During infection, Pseudomonas aeruginosa employs bacterial communication (quorum
sensing [QS]) to coordinate the expression of tissue-damaging factors. QS-controlled gene …

Multiple sensors control reciprocal expression of Pseudomonas aeruginosa regulatory RNA and virulence genes

I Ventre, AL Goodman, I Vallet-Gely… - Proceedings of the …, 2006 - National Acad Sciences
The opportunistic pathogen Pseudomonas aeruginosa is responsible for a wide range of
acute and chronic infections. The transition to chronic infections is accompanied by …

The third quorum-sensing system of Pseudomonas aeruginosa: Pseudomonas quinolone signal and the enigmatic PqsE protein

S García-Reyes, G Soberón-Chávez… - Journal of medical …, 2020 - microbiologyresearch.org
Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence
factors such as lectin A, pyocyanin, elastase and rhamnolipids. These compounds are …

The second type VI secretion system of Pseudomonas aeruginosa strain PAO1 is regulated by quorum sensing and Fur and modulates internalization in epithelial …

TG Sana, A Hachani, I Bucior, C Soscia… - Journal of Biological …, 2012 - ASBMB
The genome of Pseudomonas aeruginosa PAO1 contains three type VI secretion systems
(T6SSs) called H1-, H2-, and H3-T6SS. The H1-T6SS secretes three identified toxins that …

Evolution of resistance to quorum-sensing inhibitors

VC Kalia, TK Wood, P Kumar - Microbial ecology, 2014 - Springer
The major cause of mortality and morbidity in human beings is bacterial infection. Bacteria
have developed resistance to most of the antibiotics primarily due to large-scale and …

Quorum sensing and virulence regulation in Xanthomonas campestris

YW He, LH Zhang - FEMS microbiology reviews, 2008 - academic.oup.com
It is now clear that cell–cell communication, often referred to as quorum sensing (QS), is the
norm in the prokaryotic kingdom and this community-wide genetic regulatory mechanism …