RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

SE Castel, RA Martienssen - Nature Reviews Genetics, 2013 - nature.com
A growing number of functions are emerging for RNA interference (RNAi) in the nucleus, in
addition to well-characterized roles in post-transcriptional gene silencing in the cytoplasm …

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

RNA-directed DNA methylation

RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems

A Papikian, W Liu, J Gallego-Bartolomé… - Nature …, 2019 - nature.com
Understanding genomic functions requires site-specific manipulation of loci via efficient
protein effector targeting systems. However, few approaches for targeted manipulation of the …

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

J Gallego-Bartolomé, J Gardiner… - Proceedings of the …, 2018 - National Acad Sciences
DNA methylation is an important epigenetic modification involved in gene regulation and
transposable element silencing. Changes in DNA methylation can be heritable and, thus …

[HTML][HTML] Highly integrated single-base resolution maps of the epigenome in Arabidopsis

R Lister, RC O'Malley, J Tonti-Filippini, BD Gregory… - Cell, 2008 - cell.com
Deciphering the multiple layers of epigenetic regulation that control transcription is critical to
understanding how plants develop and respond to their environment. Using sequencing-by …

Eukaryotic cytosine methyltransferases

MG Goll, TH Bestor - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract Large-genome eukaryotes use heritable cytosine methylation to silence
promoters, especially those associated with transposons and imprinted genes. Cytosine …

Regulation and function of DNA methylation in plants and animals

XJ He, T Chen, JK Zhu - Cell research, 2011 - nature.com
DNA methylation is an important epigenetic mark involved in diverse biological processes.
In plants, DNA methylation can be established through the RNA-directed DNA methylation …

Histone methylation in higher plants

C Liu, F Lu, X Cui, X Cao - Annual review of plant biology, 2010 - annualreviews.org
Histone methylation plays a fundamental role in regulating diverse developmental
processes and is also involved in silencing repetitive sequences in order to maintain …

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

JA Law, J Du, CJ Hale, S Feng, K Krajewski… - Nature, 2013 - nature.com
DNA methylation is an epigenetic modification that has critical roles in gene silencing,
development and genome integrity. In Arabidopsis, DNA methylation is established by …