The neurochemical profile quantified by in vivo 1H NMR spectroscopy
Proton NMR spectroscopy is emerging from translational and preclinical neuroscience
research as an important tool for evidence based diagnosis and therapy monitoring. It …
research as an important tool for evidence based diagnosis and therapy monitoring. It …
Imaging devices for use in small animals
Imaging devices for small animals have emerged in the past 10 years as extraordinarily
useful tools in translational research and drug development. The Food and Drug …
useful tools in translational research and drug development. The Food and Drug …
Heteronuclear micro-Helmholtz coil facilitates µm-range spatial and sub-Hz spectral resolution NMR of nL-volume samples on customisable microfluidic chips
N Spengler, J Hoefflin, A Moazenzadeh, D Mager… - PloS one, 2016 - journals.plos.org
We present a completely revised generation of a modular micro-NMR detector, featuring an
active sample volume of∼ 100 nL, and an improvement of 87% in probe efficiency. The …
active sample volume of∼ 100 nL, and an improvement of 87% in probe efficiency. The …
Targeting protein kinase CK2: evaluating CX-4945 potential for GL261 glioblastoma therapy in immunocompetent mice
L Ferrer-Font, L Villamañan, N Arias-Ramos… - Pharmaceuticals, 2017 - mdpi.com
Glioblastoma (GBM) causes poor survival in patients even with aggressive treatment.
Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but …
Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but …
Anti-pd-1 immunotherapy in preclinical gl261 glioblastoma: Influence of therapeutic parameters and non-invasive response biomarker assessment with mrsi-based …
S Wu, P Calero-Pérez, C Arús, AP Candiota - International journal of …, 2020 - mdpi.com
Glioblastomas (GBs) are malignant brain tumours with poor prognosis even after aggressive
therapy. Programmed cell death-1 (PD-1) immune checkpoint blockade is a promising …
therapy. Programmed cell death-1 (PD-1) immune checkpoint blockade is a promising …
Tracking Therapy Response in Glioblastoma Using 1D Convolutional Neural Networks
S Ortega-Martorell, I Olier, O Hernandez… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GB) is a malignant brain tumour with no cure, even after the
best treatment. The evaluation of a therapy response is usually based on magnetic …
best treatment. The evaluation of a therapy response is usually based on magnetic …
Anti‐tumour immune response in GL261 glioblastoma generated by Temozolomide Immune‐Enhancing Metronomic Schedule monitored with MRSI‐based …
S Wu, P Calero‐Pérez, L Villamañan… - NMR in …, 2020 - Wiley Online Library
Glioblastomas (GB) are brain tumours with poor prognosis even after aggressive therapy.
Improvements in both therapeutic and follow‐up strategies are urgently needed. In previous …
Improvements in both therapeutic and follow‐up strategies are urgently needed. In previous …
Metronomic treatment in immunocompetent preclinical GL261 glioblastoma: effects of cyclophosphamide and temozolomide
L Ferrer‐Font, N Arias‐Ramos… - NMR in …, 2017 - Wiley Online Library
Glioblastoma (GBM) causes poor survival in patients even when applying aggressive
treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment …
treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment …
Convex non-negative matrix factorization for brain tumor delimitation from MRSI data
Background Pattern Recognition techniques can provide invaluable insights in the field of
neuro-oncology. This is because the clinical analysis of brain tumors requires the use of non …
neuro-oncology. This is because the clinical analysis of brain tumors requires the use of non …
Applications of high‐resolution magic angle spinning MRS in biomedical studies I—cell line and animal models
E Kaebisch, TL Fuss, LA Vandergrift… - NMR in …, 2017 - Wiley Online Library
High‐resolution magic angle spinning (HRMAS) MRS allows for direct measurements of non‐
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …