Neurodegenerative disorders (NDDs) are characterized by progressive loss of selectively
vulnerable neuronal populations and myelin sheath, leading to behavioral and cognitive …

Mitochondria are crucial organelles responsible for energy generation in eukaryotic cells.
Oxidative stress, calcium disorders, and mitochondrial DNA abnormalities can all cause …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and its
early onset is closely related to mitochondrial energy metabolism. The brain is only 2% of …

Salivary glands are indirectly damaged during radiotherapy for head and neck cancer,
resulting in acute and chronic hyposalivation. Current treatments for radiation-induced …

Regulation of the oxidative stress response is crucial for the management and prognosis of
traumatic brain injury (TBI). The copper chaperone Antioxidant 1 (Atox1) plays a crucial role …

Alzheimer's disease (AD) is characterized by the accumulation of pathological amyloid‐β
(Aβ) and Tau proteins. According to the prion‐like hypothesis, both proteins can seed and …

The frequently repeated administration of alprazolam (Alp), a highly effective
benzodiazepine sedative-hypnotic agent, in anxiety, insomnia, and other diseases is closely …

Comprehensive characterization of membrane proteins at the level of proteoforms in
complex biological samples by top-down mass spectrometry (MS) is of vital importance in …

Alzheimer's disease (AD) is a neurological disease with memory loss and cognitive decline,
which affects a large proportion of the aging population. Regrettably, there are no drug to …

Stem cells possess extraordinary capacities for self-renewal and differentiation, making
them highly valuable in regenerative medicine. Among these, neural stem cells (NSCs) play …