Pan-genomics in the human genome era
RM Sherman, SL Salzberg - Nature Reviews Genetics, 2020 - nature.com
Since the early days of the genome era, the scientific community has relied on a single
'reference'genome for each species, which is used as the basis for a wide range of genetic …
'reference'genome for each species, which is used as the basis for a wide range of genetic …
Helicobacter pylori treatment in the post-antibiotics era—searching for new drug targets
P Roszczenko-Jasińska, MI Wojtyś… - Applied Microbiology …, 2020 - Springer
Helicobacter pylori, a member of Epsilonproteobacteria, is a Gram-negative microaerophilic
bacterium that colonizes gastric mucosa of about 50% of the human population. Although …
bacterium that colonizes gastric mucosa of about 50% of the human population. Although …
Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: a reverse vaccinology based approach
Helicobacter pylori (H. pylori) is an important pathogen associated with diverse gastric
disorders ranging from peptic ulcer to malignancy. It has also been recognized by the World …
disorders ranging from peptic ulcer to malignancy. It has also been recognized by the World …
Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …
of antibiotics used against them. AR is rising to a high level across the globe, and novel …
Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against Morganella morganii
Morganella morganii is one of the main etiological agents of hospital-acquired infections
and no licensed vaccine is available against the pathogen. Herein, we designed a multi …
and no licensed vaccine is available against the pathogen. Herein, we designed a multi …
Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets
Background Acinetobacter baumannii has emerged as a significant nosocomial pathogen
during the last few years, exhibiting resistance to almost all major classes of antibiotics …
during the last few years, exhibiting resistance to almost all major classes of antibiotics …
Pan-genome analysis of oral bacterial pathogens to predict a potential novel multi-epitopes vaccine candidate
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium, mainly present in the
oral cavity and causes periodontal infections. Currently, no licensed vaccine is available …
oral cavity and causes periodontal infections. Currently, no licensed vaccine is available …
Computer-Aided Multi-Epitope Vaccine Design against Enterobacter xiangfangensis
A Alshammari, M Alharbi, A Alghamdi… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance is a global public health threat and is associated with high mortality due
to antibiotics' inability to treat bacterial infections. Enterobacter xiangfangensis is an …
to antibiotics' inability to treat bacterial infections. Enterobacter xiangfangensis is an …
Vaccinomics to design a novel single chimeric subunit vaccine for broad-spectrum immunological applications targeting nosocomial Enterobacteriaceae pathogens
Healthcare associated infections (HAIs) are major cause of elevated mortality, morbidity, and
high healthcare costs. Development of a vaccine targeting these pathogens could benefit in …
high healthcare costs. Development of a vaccine targeting these pathogens could benefit in …
Whole Genome Sequence and Phylogenetic Analysis Show Helicobacter pylori Strains from Latin America Have Followed a Unique Evolution Pathway
ZY Munoz-Ramirez, A Mendez-Tenorio… - Frontiers in cellular …, 2017 - frontiersin.org
Helicobacter pylori (HP) genetics may determine its clinical outcomes. Despite high
prevalence of HP infection in Latin America (LA), there have been no phylogenetic studies in …
prevalence of HP infection in Latin America (LA), there have been no phylogenetic studies in …