[FeFe]-Hydrogenases: maturation and reactivity of enzymatic systems and overview of biomimetic models
JT Kleinhaus, F Wittkamp, S Yadav… - Chemical Society …, 2021 - pubs.rsc.org
While hydrogen plays an ever-increasing role in modern society, nature has utilized
hydrogen since a very long time as an energy carrier and storage molecule. Among the …
hydrogen since a very long time as an energy carrier and storage molecule. Among the …
Hydrogenase enzymes and their synthetic models: the role of metal hydrides
Hydrogenase enzymes efficiently process H2 and protons at organometallic FeFe, NiFe, or
Fe active sites. Synthetic modeling of the many H2ase states has provided insight into …
Fe active sites. Synthetic modeling of the many H2ase states has provided insight into …
The catalytic cycle of [FeFe] hydrogenase: A tale of two sites
JA Birrell, P Rodriguez-Macia, EJ Reijerse… - Coordination Chemistry …, 2021 - Elsevier
Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the …
1931), their structure and mechanism of action have been intensively investigated. Of the …
Current state of [FeFe]-hydrogenase research: biodiversity and spectroscopic investigations
Hydrogenases are redox enzymes that catalyze the conversion of protons and molecular
hydrogen (H2). Based on the composition of the active site cofactor, the monometallic [Fe] …
hydrogen (H2). Based on the composition of the active site cofactor, the monometallic [Fe] …
Spectroscopic and computational evidence that [FeFe] hydrogenases operate exclusively with CO-bridged intermediates
JA Birrell, V Pelmenschikov, N Mishra… - Journal of the …, 2019 - ACS Publications
[FeFe] hydrogenases are extremely active H2-converting enzymes. Their mechanism
remains highly controversial, in particular, the nature of the one-electron and two-electron …
remains highly controversial, in particular, the nature of the one-electron and two-electron …
Protonation/reduction dynamics at the [4Fe–4S] cluster of the hydrogen-forming cofactor in [FeFe]-hydrogenases
The [FeFe]-hydrogenases of bacteria and algae are the most efficient hydrogen conversion
catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe–4S] cluster linked …
catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe–4S] cluster linked …
The molecular proceedings of biological hydrogen turnover
M Haumann, ST Stripp - Accounts of chemical research, 2018 - ACS Publications
Conspectus Over the past two decades, the bioinorganic chemistry of hydrogenases has
attracted much interest from basic and applied research. Hydrogenases are highly efficient …
attracted much interest from basic and applied research. Hydrogenases are highly efficient …
[FeFe]-Hydrogenases: recent developments and future perspectives
[FeFe]-Hydrogenases are the most efficient enzymes for catalytic hydrogen turnover. Their
H2 production efficiency is hitherto unrivalled. However, functional details of the catalytic …
H2 production efficiency is hitherto unrivalled. However, functional details of the catalytic …
[HTML][HTML] An unexpected leading role for [Fe2 (CO) 6 (μ-pdt)] in our understanding of [FeFe]-H2ases and the search for clean hydrogen production
G Hogarth - Coordination Chemistry Reviews, 2023 - Elsevier
Abstract When Ziegler and Korav serendipitously prepared [Fe 2 (CO) 6 (μ-pdt)] in 1979 they
could not have anticipated that some 40 years later it would be a mainstay of attempts to …
could not have anticipated that some 40 years later it would be a mainstay of attempts to …
Proton‐Coupled Reduction of the Catalytic [4Fe‐4S] Cluster in [FeFe]‐Hydrogenases
Abstract In nature,[FeFe]‐hydrogenases catalyze the uptake and release of molecular
hydrogen (H2) at a unique iron‐sulfur cofactor. The absence of an electrochemical …
hydrogen (H2) at a unique iron‐sulfur cofactor. The absence of an electrochemical …