The Hierarchical Taxonomy of Psychopathology (HiTOP) has emerged out of the
quantitative approach to psychiatric nosology. This approach identifies psychopathology …

The arrival of the Journal's 175th anniversary occurs at a time of recent advances in
research, providing an ideal opportunity to present a neurodevelopmental roadmap for …

Maladaptive behavior is common in Autism Spectrum Disorder (ASD). However, the factors
that give rise to maladaptive behavior in this context are not well understood. The present …

Irritability is a symptom of 15 disorders in the DSM-5 and is included in Mood Disorders,
Addictive Disorders, Personality Disorders, and more (American Psychiatric Association …

Background: Students with Autism Spectrum Disorder (ASD) commonly demonstrate
prominent social communication deficits, symptoms of attention-deficit/hyperactivity disorder …

Objectives: To date, there is no single medication prescribed to alleviate all the core
symptoms of Autism Spectrum Disorder (ASD; National Institute of Health and Care …

Objectives Characterizing the scope and import of early childhood irritability is essential for
real‐world actualization of this reliable indicator of transdiagnostic mental health risk. Thus …

Electroencephalogram-recorded epileptiform activity is common in children with autism
spectrum disorder (ASD), even without clinical seizures. A systematic literature search …

Exposure to stress during the early postnatal period (ie, early life stress, ES) can impact
brain physiology and modify individual variability in adult social behavior. Arginine …

Background As elegant structures designed for neural communication, synapses are the
building bricks of our mental functions. Recently, many studies have pointed out that …