Recent advances in tick antigen discovery and anti-tick vaccine development

MN Abbas, MA Jmel, I Mekki, I Dijkgraaf… - International Journal of …, 2023 - mdpi.com
Ticks can seriously affect human and animal health around the globe, causing significant
economic losses each year. Chemical acaricides are widely used to control ticks, which …

Rhipicephalus microplus: An overview of vaccine antigens against the cattle tick

DFS Pereira, HS Ribeiro, AAM Gonçalves… - Ticks and tick-borne …, 2022 - Elsevier
Rhipicephalus microplus, popularly known as the cattle tick, is the most important tick of
livestock as it is responsible for significant economic losses. The use of chemical acaricides …

Proteomic Analysis of Cattle Tick Rhipicephalus (Boophilus) microplus Saliva: A Comparison between Partially and Fully Engorged Females

L Tirloni, J Reck, RMS Terra, JR Martins, A Mulenga… - PloS one, 2014 - journals.plos.org
The cattle tick Rhipicephalus (Boophilus) microplus is one of the most harmful parasites
affecting bovines. Similarly to other hematophagous ectoparasites, R. microplus saliva …

Tick innate immune responses to hematophagy and Ehrlichia infection at single-cell resolution

A Adegoke, JMC Ribeiro, RC Smith… - Frontiers in …, 2024 - frontiersin.org
Introduction Ticks rely on robust cellular and humoral responses to control microbial
infection. However, several aspects of the tick's innate immune system remain …

The quest for a universal vaccine against ticks: cross-immunity insights

LF Parizi, NW Githaka, C Logullo, S Konnai… - The Veterinary …, 2012 - Elsevier
As blood-sucking parasites, ticks inflict great damage to animals and humans in many parts
of the world. The continued use of chemical acaricides is not sustainable due to increasing …

Tick innate immunity

P Kopáček, O Hajdušek, V Burešová, S Daffre - Invertebrate Immunity, 2010 - Springer
Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate
hosts. The vector competence of ticks is tightly linked with their immune system. Despite its …

Differential Expression of Ixodes ricinus Tick Genes Induced by Blood Feeding or Borrelia burgdorferi Infection

N Rudenko, M Golovchenko… - Journal of medical …, 2005 - academic.oup.com
Ixodes ricinus L. is the principal European vector of Borrelia burgdorferi sensu lato, the
causative agent of Lyme borreliosis. Subtractive hybridization was used to isolate tick genes …

[HTML][HTML] Multi-antigenic vaccine against the cattle tick Rhipicephalus (Boophilus) microplus: a field evaluation

LF Parizi, J Reck Jr, DP Oldiges, MG Guizzo, A Seixas… - Vaccine, 2012 - Elsevier
The tick Rhipicephalus (Boophilus) microplus is a blood-sucking ectoparasite of cattle that
severely impairs livestock production. Studies on tick immunological control address mostly …

[HTML][HTML] Cross immunity with Haemaphysalis longicornis glutathione S-transferase reduces an experimental Rhipicephalus (Boophilus) microplus infestation

LF Parizi, KU Utiumi, S Imamura, M Onuma… - Experimental …, 2011 - Elsevier
Recombinant Glutathione S-transferase of Haemaphysalis longicornis (rGST-Hl) was
expressed in Escherichia coli, purified by affinity chromatography and used in the …

A selenium-dependent glutathione peroxidase (Se-GPx) and two glutathione S-transferases (GSTs) from Chinese shrimp (Fenneropenaeus chinensis)

Q Ren, RR Sun, XF Zhao, JX Wang - … and Physiology Part C: Toxicology & …, 2009 - Elsevier
Glutathione S-transferases (GSTs) and glutathione peroxidases (GPxs) are essential
components of cellular detoxification systems that defend cells against reactive oxygen …