Tumor immune microenvironment lncRNAs

EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

[HTML][HTML] Sex differences in cancer mechanisms

JB Rubin, JS Lagas, L Broestl, J Sponagel… - Biology of sex …, 2020 - Springer
We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …

[HTML][HTML] Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers

Y Li, T Jiang, W Zhou, J Li, X Li, Q Wang, X Jin… - Nature …, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression
and they play fundamental roles in immune regulation. Here we introduce an integrated …

[HTML][HTML] A comprehensive pan-cancer molecular study of gynecologic and breast cancers

AC Berger, A Korkut, RS Kanchi, AM Hegde, W Lenoir… - Cancer cell, 2018 - cell.com
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of
four gynecological types plus breast. Our aims were to identify shared and unique molecular …

[HTML][HTML] The functions and unique features of LncRNAs in cancer development and tumorigenesis

K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

[HTML][HTML] The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

M Zhang, W Weng, Q Zhang, Y Wu, S Ni, C Tan… - Journal of hematology & …, 2018 - Springer
Background The long noncoding RNA nuclear-enriched abundant transcript 1 (NEAT1) has
been reported to be overexpressed in colorectal cancer (CRC). However, its underlying …

The RNA Atlas expands the catalog of human non-coding RNAs

L Lorenzi, HS Chiu, F Avila Cobos, S Gross… - Nature …, 2021 - nature.com
Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …

[HTML][HTML] Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

J Carlevaro-Fita, A Lanzós, L Feuerbach… - Communications …, 2020 - nature.com
Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating
the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains …

[HTML][HTML] Emerging roles of lncRNAs in the post-transcriptional regulation in cancer

RZ He, DX Luo, YY Mo - Genes & diseases, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …

[HTML][HTML] Before and after: comparison of legacy and harmonized TCGA genomic data commons' data

GF Gao, JS Parker, SM Reynolds, TC Silva, LB Wang… - Cell systems, 2019 - cell.com
We present a systematic analysis of the effects of synchronizing a large-scale, deeply
characterized, multi-omic dataset to the current human reference genome, using updated …