Lysosomes are membrane-bound organelles with roles in processes involved in degrading
and recycling cellular waste, cellular signalling and energy metabolism. Defects in genes …

For decades, the use of secondary metabolites of various herbs has been an attractive
strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic …

Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …

Background: Dietary fibers are metabolized by gastrointestinal (GI) bacteria into short-chain
fatty acids (SCFAs). We investigated the potential role of these SCFAs in β-amyloid (Aβ) …

Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …

Alzheimer's disease (AD) is a common neurodegenerative disorder in the elderly
characterized by memory loss and cognitive dysfunction. The pathogenesis of AD is …

Synaptic dysfunction in CNS disorders is the outcome of perturbations in physiological
synapse structure and function, and can be either the cause or the consequence in specific …

Bacopa monnieri (Brahmi) is a well-known perennial, creeping herb of the Indian Ayurveda
system; it contains numerous bioactive phytoconstituents implicated in the therapeutic …

Aggregation of RNA-binding proteins (RBPs) is a pathological hallmark of
neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and frontotemporal …

Neurodegenerative diseases are a major burden for our society, affecting millions of people
worldwide. A main goal of past and current research is to enhance our understanding of the …