Hospital-acquired diarrhoea (HAD) is common, and often associated with gut microbiota and
metabolome dysbiosis following antibiotic administration. Clostridioides difficile is the most …

Background Two-step testing for Clostridioides difficile infection (CDI) aims to improve
diagnostic specificity but may also influence reported epidemiology and patterns of …

Currently available diagnostic tests for Clostridioides difficile infection (CDI) lack specificity
or sensitivity, which has led to guideline recommendations for multistep testing algorithms …

Clostridioides difficile infection (CDI) is an important cause of morbidity and mortality
worldwide. Data from public health surveillance systems are important for estimating country …

Objectives Clostridioides difficile infection (CDI) represents a challenging issue, with an
evolving epidemiology. Main objectives of our study were: to assess the frequency of …

Objective: We evaluated the impact of test-order frequency per diarrheal episodes on
Clostridioides difficile infection (CDI) incidence estimates in a sample of hospitals at 2 CDC …

Clostridioides difficile infection (CDI) often manifests as diarrhea, particularly in adults of
older age or with underlying comorbidities. However, only severe cases are notifiable in …

Objectives This study aimed to determine the stool specimen collection and Clostridioides
difficile (C. difficile) testing frequency from inpatients and long-term care facility (LTCF) …

Clinical assessment remains fundamental to the evaluation of HCAD and targeted testing for
C. difficile is sufficient in most patients. Multiplex gastrointestinal panels may have a role in …

Summary Background & Aims Diarrhea is very common in patients receiving enteral
nutrition. The principle of diarrhea treatment involves implementing dietary modifications …