The role of surfactant in lung disease and host defense against pulmonary infections

SH Han, RK Mallampalli - Annals of the American Thoracic Society, 2015 - atsjournals.org
Pulmonary surfactant is essential for life as it lines the alveoli to lower surface tension,
thereby preventing atelectasis during breathing. Surfactant is enriched with a relatively …

Exogenous pulmonary surfactant: A review focused on adjunctive therapy for severe acute respiratory syndrome coronavirus 2 including SP-A and SP-D as added …

A Ghati, P Dam, D Tasdemir, A Kati, H Sellami… - Current opinion in …, 2021 - Elsevier
Type I and type II pneumocytes are two forms of epithelial cells found lining the alveoli in the
lungs. Type II pneumocytes exclusively secrete 'pulmonary surfactants,'a lipoprotein …

The role of angiopoietin‐2 and surfactant protein‐D levels in SARS‐CoV‐2‐related lung injury: a prospective, observational, cohort study

H Alay, E Laloglu - Journal of Medical Virology, 2021 - Wiley Online Library
Abstract Introduction Coronavirus disease‐2019 (COVID‐19) is a respiratory disease whose
clinical manifestation ranges from asymptomatic to severe respiratory failure. The purpose of …

Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection

L Salvioni, F Testa, A Sulejmani, F Pepe… - Clinica Chimica …, 2022 - Elsevier
Abstract Background Surfactant protein-D (SP-D) is a lung-resident protein that has
emerged as a potential biomarker for COVID-19. Previous investigations on acute …

The role and molecular mechanism of action of surfactant protein D in innate host defense against influenza A virus

IN Hsieh, X De Luna, MR White… - Frontiers in …, 2018 - frontiersin.org
Influenza A viruses (IAVs) continue to pose major risks of morbidity and mortality during
yearly epidemics and periodic pandemics. The genomic instability of IAV allows it to evade …

Expression of surfactant protein D distinguishes severe pandemic influenza A (H1N1) from coronavirus disease 2019

JA Choreño-Parra, LA Jiménez-Álvarez… - The Journal of …, 2021 - academic.oup.com
The differentiation between influenza and coronavirus disease 2019 (COVID-19) could
constitute a diagnostic challenge during the ongoing winter owing to their clinical similitude …

YKL‐40, CCL18 and SP‐D predict mortality in patients hospitalized with community‐acquired pneumonia

SMC Spoorenberg, SMT Vestjens, GT Rijkers… - …, 2017 - Wiley Online Library
Background and objective The aim of this study was to investigate the prognostic value of
four biomarkers, YKL‐40, chemokine (C‐C motif) ligand 18 (CCL18), surfactant protein‐D …

Correlation between serum surfactant protein-D level with respiratory compliance and acute respiratory distress syndrome in critically ill COVID-19 Patients: A …

PS Airlangga, E Kusuma, CS Waloejo… - … Journal of Critical …, 2022 - journals.lww.com
Background: Acute respiratory distress syndrome (ARDS) is one of the manifestations of
severe coronavirus disease 2019 (COVID-19) with low respiratory compliance and poor …

Circulating Surfactant Protein D: A Biomarker for Acute Lung Injury?

A Elmore, A Almuntashiri, X Wang, S Almuntashiri… - Biomedicines, 2023 - mdpi.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening
lung diseases in critically ill patients. The lack of prognostic biomarkers has halted detection …

[HTML][HTML] Correlation of surfactant Protein-D (SP-D) serum levels with ARDS severity and mortality in Covid-19 patients in Indonesia

A Agustama, AS Veterini, A Utariani - Acta medica academica, 2022 - ncbi.nlm.nih.gov
Objective. The purpose of this research was to investigate the correlation between serum
levels of surfactant protein-D (SP-D) with acute respiratory distress syndrome (ARDS) …