Future cancer research priorities in the USA: a Lancet Oncology Commission
EM Jaffee, C Van Dang, DB Agus… - The Lancet …, 2017 - thelancet.com
We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …
biology and cancer. In this era of big data, we are amassing large amounts of information …
Functional lung imaging in radiation therapy for lung cancer: A systematic review and meta-analysis
NW Bucknell, N Hardcastle, M Bressel… - Radiotherapy and …, 2018 - Elsevier
Rationale Advanced imaging techniques allow functional information to be derived and
integrated into treatment planning. Methods A systematic review was conducted with the …
integrated into treatment planning. Methods A systematic review was conducted with the …
The VAMPIRE challenge: a multi‐institutional validation study of CT ventilation imaging
Purpose CT ventilation imaging (CTVI) is being used to achieve functional avoidance lung
cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709 …
cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709 …
Results of a multi-institutional phase 2 clinical trial for 4DCT-ventilation functional avoidance thoracic radiation therapy
Purpose Radiation pneumonitis remains a major limitation in the radiation therapy treatment
of patients with lung cancer. Functional avoidance radiation therapy uses functional imaging …
of patients with lung cancer. Functional avoidance radiation therapy uses functional imaging …
Evaluating the toxicity reduction with computed tomographic ventilation functional avoidance radiation therapy
Purpose Computed tomographic (CT) ventilation imaging is a new modality that uses 4-
dimensional (4D) CT information to calculate lung ventilation. Although retrospective studies …
dimensional (4D) CT information to calculate lung ventilation. Although retrospective studies …
Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data
Purpose A new form of functional imaging has been proposed in the form of 4-dimensional
computed tomography (4DCT) ventilation. Because 4DCTs are acquired as part of routine …
computed tomography (4DCT) ventilation. Because 4DCTs are acquired as part of routine …
Functional image-guided radiotherapy planning for normal lung avoidance
For patients with lung cancer undergoing curative intent radiotherapy, functional lung
imaging can be incorporated into treatment planning to modify the dose distribution within …
imaging can be incorporated into treatment planning to modify the dose distribution within …
Robust CT ventilation from the integral formulation of the Jacobian
Computed tomography (CT) derived ventilation algorithms estimate the apparent voxel
volume changes within an inhale/exhale CT image pair. Transformation‐based methods …
volume changes within an inhale/exhale CT image pair. Transformation‐based methods …
Interim analysis of a two-institution, prospective clinical trial of 4DCT-ventilation-based functional avoidance radiation therapy
Purpose Functional imaging has been proposed that uses 4DCT images to calculate 4DCT-
based lung ventilation (4DCT-ventilation). We have started a 2-institution, phase 2 …
based lung ventilation (4DCT-ventilation). We have started a 2-institution, phase 2 …
Regional lung function profiles of stage I and III lung cancer patients: an evaluation for functional avoidance radiation therapy
Purpose The development of clinical trials is underway to use 4-dimensional computed
tomography (4DCT) ventilation imaging to preferentially spare functional lung in patients …
tomography (4DCT) ventilation imaging to preferentially spare functional lung in patients …