Inhibitor of DNA binding (ID) proteins are transcriptional regulators that control the timing of
cell fate determination and differentiation in stem and progenitor cells during normal …

The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

Inhibitors of DNA binding and cell differentiation (Id) proteins are members of the large
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …

Glioblastoma (glioblastoma multiforme; GBM; WHO Grade IV) accounts for the majority of
primary malignant brain tumors in adults. Amplification and mutation of the epidermal growth …

Despite considerable amount of research, the poor prognosis of patients diagnosed with
glioblastoma multiforme (GBM) critically needs new drug development to improve clinical …

Background Cancer stem cells are thought to be responsible for the initiation and
progression of cancers. In non-small cell lung cancers (NSCLCs), Hoechst 33342 dye …

BACKGROUND: The initiation and progression of various types of tumors, including glioma,
are driven by a population of cells with stem cell properties. Glioma stem cells (GSCs) are …

Recurrence in glioblastoma is nearly universal, and its prognosis remains dismal despite
significant advances in treatment over the past decade. Glioblastoma demonstrates …

Glioblastoma multiformes (GBMs) are extensively heterogeneous at both cellular and
molecular levels. Current therapeutic strategies include targeting of key signaling molecules …

Abstract Background Extracellular vesicles (EVs) derived from tumor cells are implicated in
the progression of malignancies through the transfer of molecular cargo microRNAs …