The development and application of optogenetics
Genetically encoded, single-component optogenetic tools have made a significant impact on
neuroscience, enabling specific modulation of selected cells within complex neural tissues …
neuroscience, enabling specific modulation of selected cells within complex neural tissues …
Optogenetic investigation of neural circuits in vivo
ME Carter, L de Lecea - Trends in molecular medicine, 2011 - cell.com
The recent development of light-activated optogenetic probes allows for the identification
and manipulation of specific neural populations and their connections in awake animals with …
and manipulation of specific neural populations and their connections in awake animals with …
Active expiration induced by excitation of ventral medulla in adult anesthetized rats
Data from perinatal and juvenile rodents support our hypothesis that the preBötzinger
complex generates inspiratory rhythm and the retrotrapezoid nucleus–parafacial respiratory …
complex generates inspiratory rhythm and the retrotrapezoid nucleus–parafacial respiratory …
Role of parafacial nuclei in control of breathing in adult rats
RTR Huckstepp, KP Cardoza… - Journal of …, 2015 - Soc Neuroscience
Contiguous brain regions associated with a given behavior are increasingly being divided
into subregions associated with distinct aspects of that behavior. Using recently developed …
into subregions associated with distinct aspects of that behavior. Using recently developed …
PreBötzinger complex neurons drive respiratory modulation of blood pressure and heart rate
Heart rate and blood pressure oscillate in phase with respiratory activity. A component of
these oscillations is generated centrally, with respiratory neurons entraining the activity of …
these oscillations is generated centrally, with respiratory neurons entraining the activity of …
Locus coeruleus activation enhances thalamic feature selectivity via norepinephrine regulation of intrathalamic circuit dynamics
We investigated locus coeruleus (LC) modulation of thalamic feature selectivity through
reverse correlation analysis of single-unit recordings from different stages of the rat vibrissa …
reverse correlation analysis of single-unit recordings from different stages of the rat vibrissa …
The integrative role of orexin/hypocretin neurons in nociceptive perception and analgesic regulation
A Inutsuka, A Yamashita, S Chowdhury, J Nakai… - Scientific reports, 2016 - nature.com
The level of wakefulness is one of the major factors affecting nociception and pain. Stress-
induced analgesia supports an animal's survival via prompt defensive responses against …
induced analgesia supports an animal's survival via prompt defensive responses against …
A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses
S Koba, N Kumada, E Narai, N Kataoka… - Nature …, 2022 - nature.com
Exercise including locomotion requires appropriate autonomic cardiovascular adjustments
to meet the metabolic demands of contracting muscles, yet the functional brain architecture …
to meet the metabolic demands of contracting muscles, yet the functional brain architecture …
Control of breathing by raphe obscurus serotonergic neurons in mice
SD DePuy, R Kanbar, MB Coates… - Journal of …, 2011 - Soc Neuroscience
We used optogenetics to determine the global respiratory effects produced by selectively
stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test …
stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test …
Wireless Self‐Powered Optogenetic System for Long‐Term Cardiac Neuromodulation to Improve Post‐MI Cardiac Remodeling and Malignant Arrhythmia
L Zhou, Y Zhang, G Cao, C Zhang, C Zheng… - Advanced …, 2023 - Wiley Online Library
Autonomic imbalance is an important characteristic of patients after myocardial infarction
(MI) and adversely contributes to post‐MI cardiac remodeling and ventricular arrhythmias …
(MI) and adversely contributes to post‐MI cardiac remodeling and ventricular arrhythmias …