Astrocytes, the largest and most numerous glial cells in the central nervous system (CNS),
play a variety of important roles in regulating homeostasis, increasing synaptic plasticity and …

Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

The blood–brain barrier (BBB) is a tightly regulated interface in the Central Nervous System
(CNS) that regulates the exchange of molecules in and out from the brain thus maintaining …

Background: Authors have been advocating the research ideology that a computer-aided
diagnosis (CAD) system trained using lots of patient data and physiological signals and …

Background Dopaminergic neuronal loss in Parkinson's disease leads to changes in the
circuitry of the basal ganglia, such as decreased inhibitory GABAergic input to the …

The term neurodegenerative disease refers to the principal pathology associated with
disorders such as amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease …

Parkinson disease (PD) is a relatively common disorder of the nervous system that afflicts
patients later in life with tremor, slowness of movement, gait instability, and rigidity …

Regulated protein turnover via the ubiquitin–proteasome system (UPS) underlies a wide
variety of signalling pathways, from cell-cycle control and transcription to development …

After more than 40 years of clinical use, levodopa (LD) remains the gold standard of
symptomatic efficacy in the drug treatment of Parkinson's disease (PD). Compared with other …

Context: Cabergoline is widely considered to be poorly effective in acromegaly. Objective:
The aim of this study was to obtain a more accurate picture of the efficacy of cabergoline in …