Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders
The visual system offers unparalleled precision in the assessment of neuroaxonal damage.
With the majority of patients with multiple sclerosis (MS) experiencing afferent and efferent …
With the majority of patients with multiple sclerosis (MS) experiencing afferent and efferent …
Paracentral acute middle maculopathy—review of the literature
N Moura-Coelho, T Gaspar, JT Ferreira… - Graefe's Archive for …, 2020 - Springer
Paracentral acute middle maculopathy (PAMM) is a recently identified spectral-domain
optical coherence tomography (SD-OCT) finding characterized by a hyper-reflective band …
optical coherence tomography (SD-OCT) finding characterized by a hyper-reflective band …
Retinal optical coherence tomography in neuromyelitis optica
FC Oertel, S Specovius, HG Zimmermann… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To determine optic nerve and retinal damage in aquaporin-4
antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a …
antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a …
Diagnosis and classification of optic neuritis
A Petzold, CL Fraser, M Abegg, R Alroughani… - The Lancet …, 2022 - thelancet.com
There is no consensus regarding the classification of optic neuritis, and precise diagnostic
criteria are not available. This reality means that the diagnosis of disorders that have optic …
criteria are not available. This reality means that the diagnosis of disorders that have optic …
Imaging the optic nerve with optical coherence tomography
HJ Shin, F Costello - Eye, 2024 - nature.com
Optical coherence tomography (OCT) is a non-invasive imaging technology, which may be
used to generate in vivo quantitative and qualitative measures of retinal structure. In terms of …
used to generate in vivo quantitative and qualitative measures of retinal structure. In terms of …
Increased serum neurofilament light and thin ganglion cell–inner plexiform layer are additive risk factors for disease activity in early multiple sclerosis
Objective To investigate the association of combined serum neurofilament light chain (sNfL)
and retinal optical coherence tomography (OCT) measurements with future disease activity …
and retinal optical coherence tomography (OCT) measurements with future disease activity …
Artificial intelligence extension of the OSCAR‐IB criteria
A Petzold, P Albrecht, L Balcer… - Annals of clinical …, 2021 - Wiley Online Library
Artificial intelligence (AI)‐based diagnostic algorithms have achieved ambitious aims
through automated image pattern recognition. For neurological disorders, this includes …
through automated image pattern recognition. For neurological disorders, this includes …
[HTML][HTML] Eye-brain connections revealed by multimodal retinal and brain imaging genetics in the UK Biobank
As an anatomical extension of the brain, the retina of the eye is synaptically connected to the
visual cortex, establishing physiological connections between the eye and the brain. Despite …
visual cortex, establishing physiological connections between the eye and the brain. Despite …
Retinal and choriocapillary vascular changes in early stages of multiple sclerosis: a prospective study
D Montorio, R Lanzillo, A Carotenuto… - Journal of Clinical …, 2021 - mdpi.com
Optical Coherence Tomography Angiography (OCTA) abnormalities occur in multiple
sclerosis (MS) over the course of the disease. OCTA investigations at early MS stages are …
sclerosis (MS) over the course of the disease. OCTA investigations at early MS stages are …
Optical coherence tomography and visual evoked potentials as prognostic and monitoring tools in progressive multiple sclerosis
S Guerrieri, G Comi, L Leocani - Frontiers in Neuroscience, 2021 - frontiersin.org
Understanding the mechanisms underlying progression and developing new treatments for
progressive multiple sclerosis (PMS) are among the major challenges in the field of central …
progressive multiple sclerosis (PMS) are among the major challenges in the field of central …