Recent insights into the roles of circular RNAs in human brain development and neurologic diseases

S Najafi, SMA Zarch, J Majidpoor, S Pordel… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

The role and clinical potentials of circular RNAs in prostate cancer

M Taheri, S Najafi, A Basiri, BM Hussen… - Frontiers in …, 2021 - frontiersin.org
Globally, prostate cancer (PCa) is the second most commonly diagnosed cancer in men
globally. Early diagnosis may help in promoting survival in the affected patients. Circular …

Insights into the multifaceted role of circular RNAs: implications for Parkinson's disease pathogenesis and diagnosis

E Doxakis - npj Parkinson's Disease, 2022 - nature.com
Parkinson's disease (PD) is a complex, age-related, neurodegenerative disease whose
etiology, pathology, and clinical manifestations remain incompletely understood. As a result …

Neuronal dysfunction and gene modulation by non-coding RNA in Parkinson's disease and synucleinopathies

R Meccariello, GC Bellenchi, S Pulcrano… - Frontiers in Cellular …, 2024 - frontiersin.org
Over the last few decades, emerging evidence suggests that non-coding RNAs (ncRNAs)
including long-non-coding RNA (lncRNA), microRNA (miRNA) and circular-RNA (circRNA) …

Circular RNA: A novel and potential regulator in pathophysiology of schizophrenia

M Singh, SLL Dwibedy, SR Biswal… - Metabolic Brain …, 2022 - Springer
Abstract Circular RNAs (CircRNAs) are a sub-class of non-coding RNA, which are covalently
closed at the ends through a non-canonical process called, backsplicing from the precursor …

Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR‐302a/E2F7 axis

X Gao, XL Wang - The Kaohsiung Journal of Medical Sciences, 2023 - Wiley Online Library
Dexmedetomidine (DEX), a common anesthetic, has significant effects on the biological
features of cancer cells. Although numerous studies have been published on the impact of …

[HTML][HTML] Diagnostic and mechanistic roles of MicroRNAs in neurodevelopmental & neurodegenerative disorders

MAS Khoodoruth, WNC Khoodoruth, M Uroos… - Neurobiology of …, 2024 - Elsevier
MicroRNAs (miRNAs) are emerging as crucial elements in the regulation of gene
expression, playing a significant role in the underlying neurobiology of a wide range of …

CircRNA and ageing

E Mahmoudi, MJ Cairns - Biochemistry and Cell Biology of Ageing: Part III …, 2023 - Springer
Circular RNAs (circRNAs) are closed-loop RNA transcripts formed by a noncanonical back
splicing mechanism. circRNAs are expressed in various tissues and cell types in a …

A unique circular RNA expression pattern in the peripheral blood of myalgic encephalomyelitis/chronic fatigue syndrome patients

Y Cheng, SM Xu, K Takenaka, G Lindner… - Gene, 2023 - Elsevier
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with
obscure aetiology. The underdiagnosis rate of ME/CFS is high due to the lack of diagnostic …