Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa
C Rezzoagli, M Archetti, I Mignot, M Baumgartner… - PLoS …, 2020 - journals.plos.org
Antibiotics are losing efficacy due to the rapid evolution and spread of resistance.
Treatments targeting bacterial virulence factors have been considered as alternatives …
Treatments targeting bacterial virulence factors have been considered as alternatives …
Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients
The development of therapies that modulate or prevent pathogen virulence may be a key
strategy for circumventing antimicrobial resistance. Toward that end, we examined the …
strategy for circumventing antimicrobial resistance. Toward that end, we examined the …
Pseudomonas aeruginosa virulence attenuation by inhibiting siderophore functions
Pseudmonas aeruginosa is a Gram-negative bacterium known to be ubiquitous and
recognized as one of the leading causes of infections such as respiratory, urinary tract …
recognized as one of the leading causes of infections such as respiratory, urinary tract …
Natural pigments of bacterial origin and their possible biomedical applications
RS Celedón, LB Díaz - Microorganisms, 2021 - mdpi.com
Microorganisms are considered one of the most promising niches for prospecting,
production, and application of bioactive compounds of biotechnological interest. Among …
production, and application of bioactive compounds of biotechnological interest. Among …
Siderophores promote cooperative interspecies and intraspecies cross-protection against antibiotics in vitro
ACM Galdino, M Vaillancourt, D Celedonio… - Nature …, 2024 - nature.com
The antibiotic cefiderocol hijacks iron transporters to facilitate its uptake and resists β-
lactamase degradation. While effective, resistance has been detected clinically with …
lactamase degradation. While effective, resistance has been detected clinically with …
Novel therapeutic strategies for treating Pseudomonas aeruginosa infection
X Shao, Y Xie, Y Zhang, J Liu, Y Ding… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Persistent infections caused by the superbug Pseudomonas aeruginosa and its
resistance to multiple antimicrobial agents are huge threats to patients with cystic fibrosis as …
resistance to multiple antimicrobial agents are huge threats to patients with cystic fibrosis as …
a dual-specificity Inhibitor targets polyphosphate kinase 1 and 2 enzymes to attenuate virulence of Pseudomonas aeruginosa
The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial
infections, which are becoming increasingly difficult to treat due to antibiotic resistance …
infections, which are becoming increasingly difficult to treat due to antibiotic resistance …
Iron acquisition and metabolism as a promising target for antimicrobials (bottlenecks and opportunities): where do we stand?
G Stelitano, M Cocorullo, M Mori, S Villa… - International Journal of …, 2023 - mdpi.com
The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections
is one of the most crucial challenges currently faced by the scientific community …
is one of the most crucial challenges currently faced by the scientific community …