Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Rhinitis is a heterogeneous condition that has been associated with inflammatory responses
as in allergic rhinitis but can also occur in the absence of inflammation such as in so‐called …

Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the
teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated …

Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic
atopy characterized by local production of specific IgE (sIgE) antibodies, a TH2 pattern of …

Background T-cell tolerance of allergic cutaneous contact sensitivity (CS) induced in mice by
high doses of reactive hapten is mediated by suppressor cells that release antigen-specific …

Chronic rhinitis is a very common disease that can be divided in various phenotypes.
Historically, the condition has been classified into the allergic rhinitis (AR) and non-allergic …

Background Local allergic rhinitis (LAR) is a common disease that affects 25.7% of the
rhinitis population and more than 47% of patients previously diagnosed with nonallergic …

Immunoglobulin E (IgE) can be highly elevated in the airway mucosa independently of IgE
serum levels and atopic status. Mostly, systemic markers are assessed to investigate …

Immunoglobulin light chain (IgLC) is a component of antibodies, but its free form is observed
in the circulation, which originates from 10 to 40% excess synthesis over heavy chain in B …