The dissemination of tumor cells to local and distant sites presents a significant challenge in
the clinical management of many solid tumors. These cells may remain dormant for months …

Extracellular matrix (ECM) plays an important role in the progression of cancer. Collagen is
the most abundant component in ECM, and it is involved in the biological formation of …

Abstract Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung
cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in …

Rationale: Subsets of patients with early-stage lung adenocarcinoma (LUAD) have a poor
post-surgical course after curative surgery. However, biomarkers stratifying this high-risk …

Gastric cancer is the third most lethal cancer worldwide, and evaluation of the genomic
status of gastric cancer cells has not translated into effective prognostic or therapeutic …

Background Lung cancer leads to the largest number of cancer-related deaths worldwide
and is usually accompanied with metastasis which is the primary cause of those death and …

Exosomes are implicated in cancer cell development, migration and invasion. Pigment
epithelium-derived factor (PEDF) is a secreted anticancer protein that can regulate lung …

Circular RNAs (circRNAs) as new types of endogenous non-coding RNAs have been
recently identified important roles in certain types of pathological responses, and in the …

Background: The potential functions of Thrombospondin 2 (THBS2) in the progression and
immune infiltration of gastric cancer (GC) remain unclear. The purpose of this study was to …

Non-small-cell lung cancer (NSCLC) is the subtype of lung cancer, which accounts for about
85% of diagnosed lung cancer cases, and is without any effective therapy. Emerging …