[HTML][HTML] Toxicity of heavy metals and recent advances in their removal: a review
MK Abd Elnabi, NE Elkaliny, MM Elyazied, SH Azab… - Toxics, 2023 - mdpi.com
Natural and anthropogenic sources of metals in the ecosystem are perpetually increasing;
consequently, heavy metal (HM) accumulation has become a major environmental concern …
consequently, heavy metal (HM) accumulation has become a major environmental concern …
Copper homeostasis and cuproptosis in cardiovascular disease therapeutics
L Yang, P Yang, GYH Lip, J Ren - Trends in pharmacological sciences, 2023 - cell.com
Copper (Cu) homeostasis is gaining increasing attention in human health as both Cu
overload and deficiency evokes pathological changes including cardiovascular diseases …
overload and deficiency evokes pathological changes including cardiovascular diseases …
[HTML][HTML] Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer
L Sun, Y Zhang, B Yang, S Sun, P Zhang, Z Luo… - Nature …, 2023 - nature.com
Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a
potential cancer therapeutic. However, the mechanisms underlying the initiation …
potential cancer therapeutic. However, the mechanisms underlying the initiation …
Early-life environmental exposures and childhood obesity: an exposome-wide approach
Background: Chemical and nonchemical environmental exposures are increasingly
suspected to influence the development of obesity, especially during early life, but studies …
suspected to influence the development of obesity, especially during early life, but studies …
Targeting cuproplasia and cuproptosis in cancer
Copper, an essential trace element that exists in oxidized and reduced forms, has pivotal
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …
[HTML][HTML] Altered metal homeostasis associates with inflammation, oxidative stress, impaired glucose metabolism, and dyslipidemia in the crosstalk between childhood …
Á González-Domínguez, M Millán-Martínez… - Antioxidants, 2022 - mdpi.com
Metals are redox-active substances that participate in central biological processes and may
be involved in a multitude of pathogenic events. However, considering the inconsistencies …
be involved in a multitude of pathogenic events. However, considering the inconsistencies …
Copper and lipid metabolism: a reciprocal relationship
Background Copper and lipid metabolism are intimately linked, sharing a complex, inverse
relationship in the periphery (outside of the central nervous system), which remains to be …
relationship in the periphery (outside of the central nervous system), which remains to be …
Extracellular Cu2+ pools and their detection: From current knowledge to next-generation probes
Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …
Copper nutrition and biochemistry and human (patho) physiology
JF Collins - Advances in food and nutrition research, 2021 - Elsevier
The essential trace mineral copper plays important roles in human physiology and
pathophysiology. Disruption of copper homeostasis may underlie the development of …
pathophysiology. Disruption of copper homeostasis may underlie the development of …
[HTML][HTML] The association between excess body mass and disturbances in somatic mineral levels
W Banach, K Nitschke, N Krajewska… - International Journal of …, 2020 - mdpi.com
Background: Obesity and excess body weight are significant epidemiological issues, not
only because they are costly to treat, but also because they are among the leading causes of …
only because they are costly to treat, but also because they are among the leading causes of …