Plant cells accumulate small RNA molecules that regulate plant development, genome
stability, and environmental responses. These small RNAs fall into three major classes …

The RNA interference (RNAi) pathway regulates mRNA stability and translation in nearly all
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …

RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Epigenetics is a discipline that studies heritable changes in gene expression that do not
involve altering the DNA sequence. Over the past decade, researchers have shown that …

The biogenesis of the RNA payload of mature sperm is of great interest, because RNAs
delivered to the zygote at fertilization can affect early development. Here, we tested the …

Inheritance of genomic DNA underlies the vast majority of biological inheritance, yet it has
been clear for decades that additional epigenetic information can be passed on to future …

One of the most significant environmental factors affecting plant growth, development and
productivity is salt stress. The damage caused by salt to plants mainly includes ionic …

The small RNA payload of mammalian sperm undergoes dramatic remodeling during
development, as several waves of microRNAs and tRNA fragments are shipped to sperm …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …