Introduction The now ubiquitous smartphone has huge potential to assist clinical decision-
making across the globe. However, the rapid pace of digitalisation contrasts starkly with the …

Background Despite unprecedented benefit from immune checkpoint inhibitors (ICIs) in
patients with mismatch repair deficient (dMMR)/microsatellite instability high (MSI-H) …

Background Estimating prognosis on the basis of clinicopathologic factors can inform clinical
practice and improve risk stratification for clinical trials. We constructed prognostic …

Simple Summary Up to 85% of patients with colorectal liver metastases develop distant
intrahepatic recurrence after curative intent local treatment.(Inter) national guidelines and …

Background TAS‐102 is indicated for patients with metastatic colorectal cancer (mCRC)
previously treated with, or not considered candidates for, available therapies. Given the …

Potential intrinsic resistance mechanisms to regorafenib were explored after short exposure
(3 days) on five CRC cell lines (HCT-116, SW1116, LS-1034, SW480, Caco-2). The …

Background The current study aimed to evaluate the serum pretreatment lactate
dehydrogenase (LDH) and overall survival (OS) in small cell lung cancer (SCLC) patients …

Background The RECOURSE trial showed clinical efficacy for trifluridine/tipiracil for
refractory metastatic colorectal cancer patients. We assessed the feasibility and …

Background On the basis of retrospective analyses and phase 2 studies, metastatic
colorectal cancer patients whose disease responded to a first-line regimen containing an …

Prognostic characterization in the initial assessment of patients with advanced cancer
disease is an essential step to plan the most appropriate therapeutic program. Since clinical …