This paper briefly reviews the physiological components of the microcirculation, focusing on
its function in homeostasis and its central function in the realization of oxygen transport to …

Clinical and pathophysiological understanding of septic shock has progressed exponentially
in the previous decades, translating into a steady decrease in septic shock-related morbidity …

Purpose Hand-held vital microscopes (HVMs) were introduced to observe sublingual
microcirculatory alterations at the bedside in different shock states in critically ill patients …

Objective Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and
a high mortality rate. The aim of this consensus is to provide support to the bedside clinician …

This article presents a personal viewpoint of the shortcoming of conventional hemodynamic
resuscitation procedures in achieving organ perfusion and tissue oxygenation following …

Objectives: Sepsis induces microvascular alterations that may play an important role in the
development of organ dysfunction. However, the relationship of these alterations to systemic …

Multiple experimental and human trials have shown that microcirculatory alterations are
frequent in sepsis. In this review, we discuss the various mechanisms that are potentially …

Background Optimal timing for the start of vasopressors (VP) in septic shock has not been
widely studied since it is assumed that fluids must be administered in advance. We sought to …

Purpose Shock is a life-threatening condition characterized by substantial alterations in the
microcirculation. This study tests the hypothesis that considering sublingual microcirculatory …

Arterial blood pressure is the driving force for organ perfusion. Although hypotension is
common in acute care, there is a lack of accepted criteria for its definition. Most practitioners …