[HTML][HTML] Clinical management of herpes simplex virus infections: past, present, and future

R Whitley, J Baines - F1000Research, 2018 - ncbi.nlm.nih.gov
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human
population. Most commonly, virus replication is limited to the epithelia and establishes …

Developments in vaccination for herpes simplex virus

R Krishnan, PM Stuart - Frontiers in microbiology, 2021 - frontiersin.org
Herpes simplex virus (HSV) is an alpha herpes virus, with two subtypes: HSV-1 and HSV-2.
HSV is one of the most prevalent sexually transmitted infections. It is the cause of severe …

A protein epitope targeted by the antibody response to Kawasaki disease

AH Rowley, SC Baker, D Arrollo… - The Journal of …, 2020 - academic.oup.com
Background Kawasaki disease (KD) is the leading cause of childhood acquired heart
disease in developed nations and can result in coronary artery aneurysms and death …

An insight into current treatment strategies, their limitations, and ongoing developments in vaccine technologies against herpes simplex infections

D Sharma, S Sharma, N Akojwar, A Dondulkar… - Vaccines, 2023 - mdpi.com
Herpes simplex virus (HSV) infection, the most prevalent viral infection that typically lasts for
a lifetime, is associated with frequent outbreaks of oral and genital lesions. Oral herpes …

“Non-essential” proteins of HSV-1 with essential roles in vivo: a comprehensive review

C Dogrammatzis, H Waisner, M Kalamvoki - Viruses, 2020 - mdpi.com
Viruses encode for structural proteins that participate in virion formation and include capsid
and envelope proteins. In addition, viruses encode for an array of non-structural accessory …

Alphaherpesvirus vaccines

CB Aschner, BC Herold - Current issues in molecular biology, 2021 - mdpi.com
Prophylactic and therapeutic vaccines for the alphaherpesviruses including varicella zoster
virus (VZV) and herpes simplex virus types 1 and 2 have been the focus of enormous …

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

CD Patel, IM Backes, SA Taylor, Y Jiang… - Science translational …, 2019 - science.org
Neonatal herpes simplex virus (nHSV) infections cause devastating morbidity and mortality
in infants. Most nHSV cases are associated with primary maternal infection, consistent with …

Mechanisms of immune control of mucosal HSV infection: A guide to rational vaccine design

NR Truong, JB Smith, KJ Sandgren… - Frontiers in …, 2019 - frontiersin.org
Herpes Simplex Virus (HSV) is a highly prevalent sexually transmitted infection that aside
from causing cold sores and genital lesions, causes complications in the …

Immune response to herpes simplex virus infection and vaccine development

AC Ike, CJ Onu, CM Ononugbo, EE Reward, SO Muo - Vaccines, 2020 - mdpi.com
Herpes simplex virus (HSV) infections are among the most common viral infections and
usually last for a lifetime. The virus can potentially be controlled with vaccines since humans …

An angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis

Y Peng, H Yang, Q Chen, H Jin, Y Xue, M Du… - Journal of Translational …, 2024 - Springer
Background Myasthenia gravis (MG) and the experimental autoimmune MG (EAMG) animal
model are characterized by T-cell-induced and B-cell-dominated autoimmune diseases that …