Gut–Brain Axis in Focus: Polyphenols, Microbiota, and Their Influence on α-Synuclein in Parkinson's Disease

E Riegelman, KS Xue, JS Wang, L Tang - Nutrients, 2024 - mdpi.com
With the recognition of the importance of the gut–brain axis in Parkinson's disease (PD)
etiology, there is increased interest in developing therapeutic strategies that target α …

Therapies for Parkinson's disease and the gut microbiome: evidence for bidirectional connection

G Hey, N Nair, E Klann, A Gurrala… - Frontiers in Aging …, 2023 - frontiersin.org
The gut brain axis (GBA), a bidirectional communication pathway has often been linked to
health and disease, and gut microbiota (GM), a key component of this pathway shown to be …

Unveiling the Interplay of AMPK/SIRT1/PGC-1α axis in Brain Health: Promising Targets Against Aging and NDDs

PS Rakshe, BJ Dutta, S Chib, N Maurya… - Ageing Research Reviews, 2024 - Elsevier
The escalating prevalence of neurodegenerative diseases (NDDs) within an aging global
population presents a pressing challenge. The multifaceted pathophysiological mechanisms …

[HTML][HTML] Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia

W Deng, P Yi, Y Xiong, J Ying, Y Lin, Y Dong… - Aging and …, 2024 - ncbi.nlm.nih.gov
The gut-brain axis is a communication channel that mediates a complex interplay of
intestinal flora with the neural, endocrine, and immune systems, linking gut and brain …

The pathogenesis of Parkinson's disease and crosstalk with other diseases.

T LIU, D GUO, J WEI - Biocell, 2024 - search.ebscohost.com
Abstract In China, Parkinson's disease (PD) is the second most prevalent central nervous
system (CNS) degenerative illness affecting middle-aged and older persons. Movement …