Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …

Facing the increasing threat of multi-drug antimicrobial resistance (AMR), humans strive to
search for antibiotic drug candidates and antibacterial alternatives from all possible places …

Mycobacterial infections are a group of life-threatening conditions triggered by fast-or slow-
growing mycobacteria. Some mycobacteria, such as Mycobacterium tuberculosis, promote …

The escalating antibiotic resistance in mycobacterial species poses a significant threat
globally, necessitating an urgent need to find alternative solutions. Bacteriophage-derived …

Emergence of antibiotic resistance in pathogenic Mycobacterium tuberculosis (Mtb) has
elevated tuberculosis to a serious global threat, necessitating alternate solutions for its …

Tuberculosis (TB) is a serious and fatal disease caused by Mycobacterium tuberculosis
(Mtb). The World Health Organization reported an estimated 1.30 million TB-related deaths …

Bacteriophages infecting Mycobacterium smegmatis mc2155 are numerous and, hence, are
classified into clusters based on nucleotide sequence similarity. Analyzing phages …

Background A large number (about 1200) of mycobacteriophages (phages) have been
isolated on Mycobacterium smegmatis mc2155. Their genome analysis shows high …

Bacteriophage endolysins are crucial for progeny release at the end of the lytic cycle.
Mycobacteriophage's genomes carry a lysin A essential gene, whose product cleaves the …

Endolysins are highly evolved bacteriophage-encoded lytic enzymes produced to damage
the bacterial cell wall for phage progeny release. They offer promising potential as highly …