Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Integration of proteomics in the molecular tumor board

J Thiery, M Fahrner - Proteomics, 2024 - Wiley Online Library
Cancer remains one of the most complex and challenging diseases in mankind. To address
the need for a personalized treatment approach for particularly complex tumor cases …

Protein biomarker discovery studies on urinary sEV fractions separated with UF-SEC for the first diagnosis and detection of recurrence in bladder cancer patients

S Jordaens, E Oeyen, H Willems, F Ameye… - Biomolecules, 2023 - mdpi.com
Urinary extracellular vesicles (EVs) are an attractive source of bladder cancer biomarkers.
Here, a protein biomarker discovery study was performed on the protein content of small …

High‐throughput molecular assays for inclusion in personalised oncology trials–State‐of‐the‐art and beyond

A Edsjö, HG Russnes, J Lehtiö… - Journal of internal …, 2024 - Wiley Online Library
In the last decades, the development of high‐throughput molecular assays has
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …

[HTML][HTML] Protein network analysis and functional enrichment via computational biotechnology unravel molecular and pathogenic mechanisms of kidney stone disease

P Peerapen, V Thongboonkerd - biomedical journal, 2023 - Elsevier
Mass spectrometry-based proteomics has been extensively applied to current biomedical
research. From such large-scale identification of proteins, several computational tools have …

Nanoparticles overcome adaptive immune resistance and enhance immunotherapy via targeting tumor microenvironment in lung cancer

X Zhang, X Wang, L Hou, Z Xu, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is one of the common malignant cancers worldwide. Immune checkpoint
inhibitor (ICI) therapy has improved survival of lung cancer patients. However, ICI therapy …

[HTML][HTML] Cerebrospinal Fluid biomarkers in pediatric brain tumors: A systematic review

KR Lehner, K Jiang, J Rincon-Torroella, R Perera… - Neoplasia, 2023 - Elsevier
Central nervous system (CNS) tumors are the leading cause of cancer death in pediatric
patients. Though these tumors typically require invasive surgical procedures to diagnose …

Metabolomics in oncology

GS Suri, G Kaur, GM Carbone, D Shinde - Cancer Reports, 2023 - Wiley Online Library
Background Oncogenic transformation alters intracellular metabolism and contributes to the
growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight …

Updates of genomics and proteomics of parathyroid carcinoma

SH Kong - Endocrines, 2022 - mdpi.com
Parathyroid carcinoma is a rare disease that needs an additional diagnostic tool and wide
therapeutic options. The genomics and proteomics approach may help to find the tools to …

Mass Spectrometry-Based Proteomics of Poly (methylmethacrylate)-Embedded Bone

A Topitsch, T Halstenbach, R Rothweiler… - Journal of Proteome …, 2024 - ACS Publications
Liquid chromatography-tandem mass spectrometry (LC–MS/MS) is a widely employed
technique in proteomics research for studying the proteome biology of various clinical …