More and more evidence shows how brain energy metabolism is the linkage between
physiological and morphological synaptic plasticity and memory consolidation. Different …

Learning and memory are fundamental but highly complex functions of the brain. They rely
on multiple mechanisms including the processing of sensory information, memory formation …

The classical view of astrocytes is that they provide supportive functions for neurons,
transporting metabolites and maintaining the homeostasis of the extracellular milieu. This …

The accumulation of metabolites in the intervertebral disc is considered an important cause
of intervertebral disc degeneration (IVDD). Lactic acid, which is a metabolite that is produced …

While neurons have traditionally been considered the primary players in information
processing, the role of astrocytes in this mechanism has largely been overlooked due to …

The astrocyte-neuron lactate shuttle (ANLS) model posits that astrocyte-generated lactate is
transported to neurons to fuel memory processes. However, neurons express high levels of …

Lactate was initially thought of as a fatigue substance. In recent years, however, lactate not
only functions as an energy carrier and contributes to ATP production, but also its role as a …

More and more evidence shows how brain energy metabolism is the linkage between
physiological and morphological synaptic plasticity and memory consolidation. Different …

Astrocytes support and modulate neuronal activity through the release of L-lactate. The
suggested roles of astrocytic lactate in the brain encompass an expanding range of vital …

The accumulation of metabolites in the intervertebral disc is considered to be an important
cause of intervertebral disc degeneration (IVDD). Lactate, which is a metabolite that is …