The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Chemotherapy, a major strategy for cancer treatment, lacks the specificity to localize the
cancer therapeutics in the tumor site, thereby affecting normal healthy tissues and …

Research on nanomedicines has rapidly progressed in the past few years. However, due to
the limited size of nuclear pores (9–12 nm), the nuclear membrane remains a difficult barrier …

Nanomaterials self-assembled from amphiphilic functional copolymers have emerged as
safe and efficient nanocarriers for delivery of therapeutics. Surface engineering of the …

Although siRNA-based nanomedicines hold promise for cancer treatment, conventional
siRNA–polymer complex (polyplex) nanocarrier systems have poor pharmacokinetics …

Severe side effects and poor therapeutic efficacy are the main drawbacks of current
anticancer drugs. These problems can be mitigated by targeting, but the targeting efficacy of …

Gene and nucleic acid delivery constitute a huge biological challenge and several attempts
have been made by research laboratories to address this issue. Cationic polymers and …

We report the synthesis of phosphorylated polyesters by the phosphorylation of hydroxylated
polyesters synthesized by the lipase-catalyzed polycondensation of glycerol and aliphatic …

Novel biomimetic amphiphilic chitosan derivative, deoxycholic acid–phosphorylcholine–
chitosan conjugate (DCA–PCCs) was synthesized based on the combination of Atherton …

Polymer micelles for anticancer drug delivery have shown many advantages. In this study,
poly (ε-caprolactone)-b-poly (2-methacryloyloxyethyl phosphorylcholine)(PCL-PMPC) with …