The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic
effects in multiple organs including brain, heart, and skeletal muscle by serving as an …

Ingesting exogenous ketone bodies has been touted as producing ergogenic effects by
altering substrate metabolism; however, research findings from recent studies appear …

Available evidence indicates that ketone bodies inhibit glycolysis in contracting muscles.
Therefore, we investigated whether acute exogenous ketosis by oral ketone ester (KE) …

A ketogenic diet (KD) could induce nutritional ketosis. Over time, the body will acclimate to
use ketone bodies as a primary fuel to achieve keto-adaptation. Keto-adaptation may …

The ketogenic diet (KD) is a high-fat, low-carbohydrate treatment for medically intractable
epilepsy. One of the hallmark features of the KD is the production of ketone bodies which …

Purpose: To determine the acute effects of ketone supplementation on exercise performance
(primary outcome) and physiological and perceptual responses to exercise (secondary …

Alzheimer's disease (AD) is a devastating neurodegenerative disease with growing
prevalence as the global population ages. Currently available treatments for AD have …

Numerous oral ketone supplements are marketed with the claim that they will rapidly induce
ketosis and improve exercise performance. The purpose of this study was to assess exercise …

There is growing interest in the effect of exogenous ketone body supplementation on
exercise responses and performance. The limited studies to date have yielded equivocal …

Background Interest into the health, disease, and performance impact of exogenous ketone
bodies has rapidly expanded due to their multifaceted physiological and signaling …