Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Display of heterologous proteins on the surface of micro‐organisms, enabled by means of
recombinant DNA technology, has become an increasingly popular strategy in microbiology …

Pneumococcus is one of the most important human pathogens that causes life-threatening
invasive diseases, especially at the extremities of age. Capsular polysaccharides (CPSs) …

For the design of potent subunit vaccines, it is of paramount importance to identify all
antigens immunologically recognized by a patient population infected with a pathogen. We …

A robust bacterial display methodology was developed that allows the rapid isolation of
peptides that bind to arbitrarily selected targets with high affinity. To demonstrate the utility of …

A variety of expression systems for the display of either short peptides or fully folded proteins
on E. coli and, to a lesser extent, on Gram‐positive bacteria have been developed. The …

A bacterial display methodology was developed for N‐and C‐terminal display and
demonstrated to enable rapid screening of very large peptide libraries with high precision …

The identification of ligands from large biological libraries by phage display has now been
used for almost 15 years. Most of the successful reports on high‐affinity ligand identification …

Advanced techniques for observing protein localization in live bacteria show that the
distributions are dynamic. For technical reasons, most such techniques have not been …

Bacteriophages are more abundant than any other organism on our planet. The interaction
of bacteriophages and bacteria and their coevolution is well known. In this chapter, we …