[HTML][HTML] Multiple sclerosis: pathogenesis, symptoms, diagnoses and cell-based therapy
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous
system (CNS) lesions that can lead to severe physical or cognitive disability as well as …
system (CNS) lesions that can lead to severe physical or cognitive disability as well as …
Animal models of multiple sclerosis
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) which involves a complex interaction between immune system and neural …
system (CNS) which involves a complex interaction between immune system and neural …
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
JM Fletcher, SJ Lalor, CM Sweeney… - Clinical & …, 2010 - academic.oup.com
Multiple sclerosis (MS) is a demyelinating inflammatory disorder of the central nervous
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …
Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases
JH Buckner - Nature Reviews Immunology, 2010 - nature.com
A lack of regulatory T (TReg) cells that express CD4, CD25 and forkhead box P3 (FOXP3)
results in severe autoimmunity in both mice and humans. Since the discovery of TReg cells …
results in severe autoimmunity in both mice and humans. Since the discovery of TReg cells …
Multiple sclerosis: pathogenesis and treatment
I Loma, R Heyman - Current neuropharmacology, 2011 - ingentaconnect.com
Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease of the
central nervous system. It affects approximately 400,000 people in the United States and …
central nervous system. It affects approximately 400,000 people in the United States and …
Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination
A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …
Regulatory T cells in autoimmune neuroinflammation
M Kleinewietfeld, DA Hafler - Immunological reviews, 2014 - Wiley Online Library
Regulatory T cells are the central element for the maintenance of peripheral tolerance.
Several subtypes of regulatory T (Treg) cells have been described, and most of them belong …
Several subtypes of regulatory T (Treg) cells have been described, and most of them belong …
Compromised CD4+ CD25high regulatory T‐cell function in patients with relapsing‐remitting multiple sclerosis is correlated with a reduced frequency of FOXP3 …
K Venken, N Hellings, M Thewissen, V Somers… - …, 2008 - Wiley Online Library
Summary CD4+ CD25high regulatory T cells (Tregs) of patients with relapsing‐remitting
(RR) multiple sclerosis (MS), in contrast to those of patients with secondary progressive (SP) …
(RR) multiple sclerosis (MS), in contrast to those of patients with secondary progressive (SP) …
Multiple sclerosis and T lymphocytes: an entangled story
L Legroux, N Arbour - Journal of Neuroimmune Pharmacology, 2015 - Springer
Multiple sclerosis (MS) is the prototypic inflammatory disease of the central nervous system
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …
Modeling the heterogeneity of multiple sclerosis in animals
SB Simmons, ER Pierson, SY Lee, JM Goverman - Trends in immunology, 2013 - cell.com
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system (CNS) manifested with varying clinical course, pathology, and inflammatory patterns …
system (CNS) manifested with varying clinical course, pathology, and inflammatory patterns …