Cardiotoxic effects of anthracycline-based therapy: what is the evidence and what are the potential harms?

BE Levis, PF Binkley, CL Shapiro - The Lancet Oncology, 2017 - thelancet.com
Despite the known cardiotoxic effects of doxorubicin and other anthracyclines, no evidence-
based guidelines exist for the surveillance and prevention of chemotherapy-induced …

Risk factors for anthracycline-induced cardiotoxicity

S Qiu, T Zhou, B Qiu, Y Zhang, Y Zhou, H Yu… - Frontiers in …, 2021 - frontiersin.org
Background: Several cardiovascular risk factors have been suggested to be associated with
anthracycline-induced cardiotoxicity, but their quantitative effects have not reached a …

Left ventricular dysfunction in cancer treatment: is it relevant?

B Kenigsberg, A Wellstein, A Barac - JACC: Heart Failure, 2018 - jacc.org
Contemporary cancer therapies have dramatically improved cancer-free and overall survival
but have been accompanied by increasing cancer treatment–related cardiovascular toxicity …

Risk factors from Framingham risk score for anthracyclines cardiotoxicity in breast cancer: A systematic review and meta-analysis

H Jin, J Xu, Z Sui, L Wang - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Background Framingham risk score (FRS) is an effective tool for evaluating the 10-year risk
of cardiovascular diseases. However, the sensitivity of FRS for anthracycline-induced …

Examining the cost-effectiveness of baseline left ventricular function assessment among breast cancer patients undergoing anthracycline-based therapy

MM Abu-Khalaf, A Safonov, J Stratton, S Wang… - Breast Cancer Research …, 2019 - Springer
Background There is a lack of consensus to guide which breast cancer patients require left
ventricular function assessment (LVEF) prior to anthracycline therapy; the cost-effectiveness …

The clinical utility of baseline cardiac assessments prior to adjuvant anthracycline chemotherapy in breast cancer: a systematic review and meta-analysis

P O'Brien, K Matheson, A Jeyakumar… - Breast Cancer Research …, 2019 - Springer
Background Cardiac assessment with multi-gated acquisition scan (MUGA) or
echocardiography (ECHO) is commonly employed prior to adjuvant anthracycline-based …

Utility of routine pretreatment evaluation of left ventricular ejection fraction in breast cancer patients receiving anthracyclines

P Peddi, SR Master, AD Dwary, HP Ravipati… - The Breast …, 2019 - Wiley Online Library
Anthracycline‐based chemotherapy is widely used in the management of breast cancer.
Despite the lack of clinical evidence, obtaining prechemotherapy left ventricular ejection …

Avaliação da Cardiotoxicidade induzida por Quimioterapia em pacientes com Câncer de Mama

IL Argani, C Arruda, J Schoueri, M Scaff… - Clinical Oncology …, 2019 - app.periodikos.com.br
Objetivo: Avaliar a alteração da função cardíaca em pacientes com câncer de mama
tratadas com quimioterapia. Métodos: Estudo observacional retrospectivo com coleta de …

[PDF][PDF] Anthracycline and Trastuzumab-Based Therapy in Early Stage Breast Cancer: Do the Data Justify Cardiac Surveillance?

N Berger, CL Shapiro - Journal of Cardiology and …, 2018 - cardiologyresearchjournal.com
Introduction Anthracycline-based and trastuzumab-containing regimens make a significant
impact on reducing the risk of distant metastases and improving cause-specific and overall …

Geriatric Cardio-oncology

A Blaes, C Shenoy - Cardio-Oncology: The Clinical Overlap of Cancer and …, 2017 - Springer
As cancer therapies improve and the population as a whole ages, the number of elderly
patients with cancer rises. Aging cancer patients are particularly vulnerable to cardiotoxicity …