A systematic review of quality of life in head and neck cancer treated with surgery with or without adjuvant treatment

S Rathod, J Livergant, J Klein, I Witterick, J Ringash - Oral oncology, 2015 - Elsevier
Quality of life (QoL) is an important consideration in the management of head and neck
cancers (HNC). We systematically reviewed the literature to assess the impact of curative …

The epidemiology of oral human papillomavirus infection in healthy populations: a systematic review and meta-analysis

S Tam, S Fu, L Xu, KJ Krause, DR Lairson, H Miao… - Oral oncology, 2018 - Elsevier
Human papillomavirus (HPV) is a potentially oncogenic sexually transmitted infection. As the
incidence of oropharyngeal cancer (OPC) caused by oral HPV infections is rising, further …

Senescence, necrosis, and apoptosis govern circulating cell-free DNA release kinetics

A Rostami, M Lambie, WY Caberry, V Stambolic… - Cell reports, 2020 - cell.com
The kinetics of circulating cell-free DNA (cfDNA) release may provide a real-time
assessment of induced cell death. However, there is a limited understanding of the …

Phase II evaluation of aggressive dose de-escalation for adjuvant chemoradiotherapy in human papillomavirus–associated oropharynx squamous cell carcinoma

DJ Ma, KA Price, EJ Moore, SH Patel… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The purpose of this study was to determine if dose de-escalation from 60 to 66
Gy to 30 to 36 Gy of adjuvant radiotherapy (RT) for selected patients with human …

HPV positive head and neck cancers: molecular pathogenesis and evolving treatment strategies

R Dok, S Nuyts - Cancers, 2016 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that
is the result of tobacco and/or alcohol abuse or infection with high-risk Human …

The incidence, clearance and persistence of non-cervical human papillomavirus infections: a systematic review of the literature

S Taylor, E Bunge, M Bakker, X Castellsagué - BMC infectious diseases, 2016 - Springer
Background Human papillomavirus (HPV) vaccines were designed to prevent cervical
cancer in women and their provision remains a major public health need. However, HPV is …

The PD‐1/PD‐L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: a multicentre study of the German Cancer …

P Balermpas, F Rödel, M Krause… - … journal of cancer, 2017 - Wiley Online Library
We examined the prognostic role of PD‐1+ and CD8+ tumor infiltrating lymphocytes (TILs),
and PD‐L1+ cells in patients with squamous cell carcinoma of the head and neck (SCCHN) …

Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy

P Balermpas, D Martin, U Wieland… - …, 2017 - Taylor & Francis
We examined the prognostic role of immune markers programmed cell death protein-1 (PD-
1) and its ligand (PD-L1), CD8+ tumor-infiltrating lymphocytes (TILs), FOXP3+ Tregs and …

Evaluation of prexasertib, a checkpoint kinase 1 inhibitor, in a phase Ib study of patients with squamous cell carcinoma

DS Hong, K Moore, M Patel, SC Grant, HA Burris III… - Clinical Cancer …, 2018 - AACR
Purpose: Prexasertib, a checkpoint kinase 1 inhibitor, demonstrated single-agent activity in
patients with advanced squamous cell carcinoma (SCC) in the dose-escalation portion of a …

[HTML][HTML] Human papillomavirus tumor infection in esophageal squamous cell carcinoma

EB Ludmir, SJ Stephens, M Palta… - Journal of …, 2015 - ncbi.nlm.nih.gov
The association between human papillomavirus (HPV) and esophageal squamous cell
carcinoma (ESCC) has been recognized for over three decades. Recently, multiple meta …