Green tea catechins attenuate neurodegenerative diseases and cognitive deficits

O Afzal, MH Dalhat, ASA Altamimi, R Rasool… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases exert an overwhelming socioeconomic burden all around the
globe. They are mainly characterized by modified protein accumulation that might trigger …

Prenatal and postnatal choline supplementation in fetal alcohol spectrum disorder

AM Ernst, BA Gimbel, E de Water, JK Eckerle… - Nutrients, 2022 - mdpi.com
Fetal alcohol spectrum disorder (FASD) is common and represents a significant public
health burden, yet very few interventions have been tested in FASD. Cognitive deficits are …

Enhancing fetal alcohol spectrum disorders diagnosis with a classifier based on the intracerebellar gradient of volumetric undersizing

J Fraize, C Fischer, M Elmaleh‐Bergès… - Human Brain …, 2023 - Wiley Online Library
In fetal alcohol spectrum disorders (FASD), brain growth deficiency is a hallmark of subjects
both with fetal alcohol syndrome (FAS) and with non‐syndromic FASD (NS‐FASD, ie, those …

[HTML][HTML] Organoids and organoids-on-a-chip as the new testing strategies for environmental toxicology-applications & advantages

C Hu, S Yang, T Zhang, Y Ge, Z Chen, J Zhang… - Environment …, 2024 - Elsevier
An increasing number of harmful environmental factors are causing serious impacts on
human health, and there is an urgent need to accurately identify the toxic effects and …

Longitudinal effects of prenatal alcohol exposure on visual neurodevelopment over infancy.

ET Margolis, L Davel, NJ Bourke, C Bosco… - Developmental …, 2024 - psycnet.apa.org
Prenatal alcohol exposure (PAE) affects neurodevelopment in over 59 million individuals
globally. Prior studies using dichotomous categorization of alcohol use and comorbid …

Therapeutic effects of catechins in less common neurological and neurodegenerative disorders

G Sebastiani, L Almeida-Toledano, M Serra-Delgado… - Nutrients, 2021 - mdpi.com
In recent years, neurological and neurodegenerative disorders research has focused on
altered molecular mechanisms in search of potential pharmacological targets, eg …

Epigallocatechin gallate ameliorates the effects of prenatal alcohol exposure in a fetal alcohol spectrum disorder-like mouse model

L Almeida-Toledano, V Andreu-Fernández… - International Journal of …, 2021 - mdpi.com
Fetal alcohol spectrum disorder is the main preventable cause of intellectual disability in the
Western world. Although binge drinking is the most studied prenatal alcohol exposure …

Fetal alcohol spectrum disorder and iron homeostasis

R Bradley, KL Lakpa, M Burd, S Mehta, MZ Katusic… - Nutrients, 2022 - mdpi.com
Prenatal alcohol exposure results in a spectrum of behavioral, cognitive, and morphological
abnormalities collectively referred to as fetal alcohol spectrum disorder (FASD). FASD …

Environmental enrichment enhances cerebellar compensation and develops cerebellar reserve

F Gelfo, L Petrosini - … Journal of Environmental Research and Public …, 2022 - mdpi.com
The brain is able to change its structure and function in response to environmental
stimulations. Several human and animal studies have documented that enhanced …

Prenatal influences on postnatal neuroplasticity: Integrating DOHaD and sensitive/critical period frameworks to understand biological embedding in early development

ET Margolis, LJ Gabard‐Durnam - Infancy, 2024 - Wiley Online Library
Early environments can have significant and lasting effects on brain, body, and behavior
across the lifecourse. Here, we address current research efforts to understand how …