During angiogenesis, new vessels emerge from existing endothelial lined vessels to
promote the degradation of the vascular basement membrane and remodel the extracellular …

There are concepts in science that need time to overcome initial disbelief before finally
arriving at the moment when they are embraced by the research community. One of these …

Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway
blockade is a promising new cancer therapy. Although PD-1/PD-L1 treatment has yielded …

Exosomes have great potential to be drug delivery vehicles due to their natural material
transportation properties, intrinsic long-term circulatory capability, and excellent …

In recent years, extracellular vesicles (EVs) have become a subject of intense study. These
membrane-enclosed spherical structures are secreted by almost every cell type and are …

Abstract Background Extracellular vesicles (EVs) are naturally occurring membrane particles
that mediate intercellular communication by delivering molecular information between cells …

Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

Intratumoral hypoxia is a common finding in breast cancer and is associated with a
significantly increased risk of metastasis and patient mortality. Hypoxia-inducible factors …

To date, extracellular vesicles (EVs) have been extensively investigated as potential
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …

Background Exosomes are nanovesicles secreted by tumour cells which have roles in
paracrine signalling during tumour progression, including tumour-stromal interactions …