B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin

CA Calderón‐Ospina… - CNS neuroscience & …, 2020 - Wiley Online Library
Background Neurotropic B vitamins play crucial roles as coenzymes and beyond in the
nervous system. Particularly vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) …

Alcohol use and dementia: a systematic scoping review

J Rehm, OSM Hasan, SE Black, KD Shield… - Alzheimer's research & …, 2019 - Springer
Background Alcohol use has been identified as a risk factor for dementia and cognitive
decline. However, some patterns of drinking have been associated with beneficial effects …

The role of neurotropic B vitamins in nerve regeneration

S Baltrusch - BioMed Research International, 2021 - Wiley Online Library
Damage and regeneration naturally occur in the peripheral nervous system. The neurotropic
B vitamins thiamine (B1), pyridoxine (B6), and cobalamin (B12) are key players, which …

Alcohol addiction, gut microbiota, and alcoholism treatment: a review

SC Wang, YC Chen, SJ Chen, CH Lee… - International journal of …, 2020 - mdpi.com
Alcohol addiction is a leading risk factor for personal death and disability. In 2016, alcohol
use caused 2.2% of female deaths and 6.8% of male deaths, and disability-adjusted life …

The phenotypic legacy of admixture between modern humans and Neandertals

CN Simonti, B Vernot, L Bastarache, E Bottinger… - Science, 2016 - science.org
Many modern human genomes retain DNA inherited from interbreeding with archaic
hominins, such as Neandertals, yet the influence of this admixture on human traits is largely …

[HTML][HTML] Neurological, psychiatric, and biochemical aspects of thiamine deficiency in children and adults

S Dhir, M Tarasenko, E Napoli, C Giulivi - Frontiers in psychiatry, 2019 - frontiersin.org
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of
enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are …

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses

A Topiwala, C Wang, KP Ebmeier, S Burgess… - PLoS …, 2022 - journals.plos.org
Background Brain iron deposition has been linked to several neurodegenerative conditions
and reported in alcohol dependence. Whether iron accumulation occurs in moderate …

Comprehensive review of Wernicke encephalopathy: pathophysiology, clinical symptoms and imaging findings

Y Ota, AA Capizzano, T Moritani, S Naganawa… - Japanese journal of …, 2020 - Springer
Wernicke's encephalopathy (WE) is a severe and life-threatening illness resulting from
vitamin B1 (thiamine) deficiency. The prevalence of WE has been estimated from 0.4 to …

Clinical and pathological features of alcohol-related brain damage

NM Zahr, KL Kaufman, CG Harper - Nature Reviews Neurology, 2011 - nature.com
One of the sequelae of chronic alcohol abuse is malnutrition. Importantly, a deficiency in
thiamine (vitamin B1) can result in the acute, potentially reversible neurological disorder …

Review of thiamine deficiency disorders: Wernicke encephalopathy and Korsakoff psychosis

A Chandrakumar, A Bhardwaj… - Journal of basic and …, 2019 - degruyter.com
Wernicke encephalopathy (WE) and Korsakoff psychosis (KP), together termed Wernicke–
Korsakoff syndrome (WKS), are distinct yet overlapping neuropsychiatric disorders …