Metal-free multicomponent syntheses of pyridines

C Allais, JM Grassot, J Rodriguez… - Chemical …, 2014 - ACS Publications
They react according to a succession of mono-or bimolecular processes to form at the end
one product that incorporates important portions and functionalities of the starting materials …

Magnetic cellulose/Ag as a novel eco-friendly nanobiocomposite to catalyze synthesis of chromene-linked nicotinonitriles

A Maleki, H Movahed, P Ravaghi - Carbohydrate polymers, 2017 - Elsevier
In this work, design, preparation and performance of magnetic cellulose/Ag
nanobiocomposite as a recyclable and highly efficient heterogeneous nanocatalyst is …

Chemistry of 2-Amino-3-cyanopyridines

MA Gouda, MA Berghot, GE Abd El Ghani… - Synthetic …, 2014 - Taylor & Francis
This review presents a systematic and comprehensive survey of the method of preparation
and the chemical reactivity of 2-amino-3-cyanopyridines. The target compounds are …

Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1

T Murata, M Shimada, S Sakakibara, T Yoshino… - Bioorganic & medicinal …, 2003 - Elsevier
IκB kinase β (IKK-β) is a serine-threonine protein kinase critically involved in the activation of
the transcription factor Nuclear Factor kappa B (NF-κB) in response to various inflammatory …

Pyridine Derivatives as Insecticides─Part 4: Synthesis, Crystal Structure, and Insecticidal Activity of Some New Thienylpyridines, Thienylthieno[2,3-b]pyridines, and …

EA Bakhite, S Abuelhassan, MA Gad… - Journal of Agricultural …, 2023 - ACS Publications
The reaction of ethyl 5-cyano-2-methyl-4-(thiophen-2-yl)-6-thioxo-1, 6-dihydropyridine-3-
carboxylate (1) with 2-chloroacetamide or its N-aryl derivatives gave ethyl 6-((2-amino-2 …

Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5, 6, 7, 8-tetrahydroquinoline-3-carbonitrile and its analogues

AR Gholap, KS Toti, F Shirazi, R Kumari… - Bioorganic & medicinal …, 2007 - Elsevier
A series of 2-amino-5-oxo-4-phenyl-5, 6, 7, 8-tetrahydroquinoline-3-carbonitrile and various
analogues have been synthesized in excellent isolated yields starting from various …

Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety

MR Shaaban, TS Saleh, AS Mayhoub… - Bioorganic & medicinal …, 2008 - Elsevier
A series of pyrazolo [1, 5-a] pyrimidine, triazolo [1, 5-a] pyrimidine, and pyrimido [1, 2-a]
benzimidazole ring systems incorporating phenylsulfonyl moiety were synthesized via the …

Anti-inflammatory, analgesic and antipyretic 4, 6-disubstituted 3-cyano-2-aminopyridines

F Manna, F Chimenti, A Bolasco, B Bizzarri… - European journal of …, 1999 - Elsevier
4, 6-diaryl and 4, 6-aryl-indolyl substituted 3-cyano-2-aminopyridines were synthesized and
submitted to evaluation for their anti-inflammatory, analgesic and antipyretic activity. The …

Novel triazolothiadiazole and triazolothiadiazine derivatives containing pyridine moiety: design, synthesis, bactericidal and fungicidal activities

RM Abdelhameed, HA El-Sayed… - Current Bioactive …, 2018 - ingentaconnect.com
Background: One of the important chemical agents in designing of anti-convulsant,
antiatherosclerotic and anti-cancer drugs are pyridine derivatives. Alkyl and aryl derivatives …

Syntheses and Biological Activities of Chalcone and 1,5‐Benzothiazepine Derivatives: Promising New Free‐Radical Scavengers, and Esterase, Urease, and α …

FL Ansari, S Umbreen, L Hussain… - Chemistry & …, 2005 - Wiley Online Library
Abstract A series of 2, 4‐diaryl‐2, 3, 4, 5‐tetrahydro‐(36–40) and 2, 4‐diaryl‐2, 3‐dihydro‐1,
5‐benzothiazepines (25–35) have been synthesized from the corresponding chalcones 1 …