Asthma is the most prevalent chronic respiratory disease both in children and adults and
resembles a complex syndrome rather than a single disease. Different methods have been …

This article reviews epidemiological evidence of heritability and putative mechanisms in
diverticular disease, with greatest attention to 3 recent studies of genetic associations with …

MicroRNAs (miRNAs) regulate post-transcriptional gene expression and may be exported
from cells via exosomes or in partnership with RNA-binding proteins. MiRNAs in body fluids …

The study was approved by the Institutional Review Boards at Children's Hospital Boston
and Brigham and Women's and Connolly Hospitals. All 18 subjects provided written …

Background Asthma is the most common chronic inflammatory disorder in children. The
aetiology of asthma pathology is complex and highly heterogeneous, involving the interplay …

BACKGROUND: The T cell–specific T-box transcription factor (TBX21) plays a crucial role in
the regulation of the immune system because this factor induces the differentiation of TH1 …

Gene–environmental interaction in the development of atopic... : Current Opinion in Allergy and
Clinical Immunology Gene–environmental interaction in the development of atopic asthma …

The year 2009 was marked by rapid progress in understanding cellular and chemical
mechanisms in the pathogenesis of asthma and other allergic disorders. Studies published …

The emergence of a novel H1N1 influenza virus in early 2009 dominated the headlines and
caused much fear worldwide as the Centers for Disease Control (CDC) proclaimed a …

Objective CLCA1 is a secreted protein with protease activity, and its expression is
associated with inflammatory airway diseases. This study aimed to investigate the role of …