Cerebral edema formation after stroke: emphasis on blood–brain barrier and the lymphatic drainage system of the brain

S Chen, L Shao, L Ma - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …

CNS-draining meningeal lymphatic vasculature: roles, conundrums and future challenges

SP das Neves, N Delivanoglou… - Frontiers in …, 2021 - frontiersin.org
A genuine and functional lymphatic vascular system is found in the meninges that sheath the
central nervous system (CNS). This unexpected (re) discovery led to a reevaluation of CNS …

Crosstalk between Inflammation and the BBB in Stroke

Y Huang, S Chen, Y Luo, Z Han - Current neuropharmacology, 2020 - ingentaconnect.com
The blood-brain barrier (BBB), which is located at the interface between the central nervous
system (CNS) and the circulatory system, is instrumental in establishing and maintaining the …

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of …

E Zinchenko, N Navolokin, A Shirokov… - Biomedical optics …, 2019 - opg.optica.org
In this pilot study, we analyzed effects of transcranial photobiomodulation (tPBM, 1267 nm,
32 J/cm^ 2) on clearance of beta-amyloid (Aβ) from the mouse brain. The …

A clinical primer for the glymphatic system

LP Carlstrom, A Eltanahy, A Perry, AA Rabinstein… - Brain, 2022 - academic.oup.com
The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …

Sleep as a novel biomarker and a promising therapeutic target for cerebral small vessel disease: A review focusing on Alzheimer's disease and the blood-brain barrier

O Semyachkina-Glushkovskaya, D Postnov… - International journal of …, 2020 - mdpi.com
Cerebral small vessel disease (CSVD) is a leading cause of cognitive decline in elderly
people and development of Alzheimer's disease (AD). Blood–brain barrier (BBB) leakage is …

Photobiomodulation of lymphatic drainage and clearance: perspective strategy for augmentation of meningeal lymphatic functions

O Semyachkina-Glushkovskaya… - Biomedical optics …, 2020 - opg.optica.org
There is a hypothesis that augmentation of the drainage and clearing function of the
meningeal lymphatic vessels (MLVs) might be a promising therapeutic target for preventing …

Modified wavelet analysis of ECoG-pattern as promising tool for detection of the blood–brain barrier leakage

A Runnova, M Zhuravlev, R Ukolov, I Blokhina… - Scientific reports, 2021 - nature.com
A new approach for detection oscillatory patterns and estimation of their dynamics based by
a modified CWT skeleton method is presented. The method opens up additional …

The oxygen saturation in the primary motor cortex during a single hand movement: functional near-infrared spectroscopy (fnirs) study

S Kurkin, A Badarin, V Grubov… - … Physical Journal Plus, 2021 - epjplus.epj.org
Functional near-infrared spectroscopy is a noninvasive optical imaging technique to register
brain activity. It utilizes near-infrared light to evaluate the oxygenated (HbO) and …

[HTML][HTML] EEG biomarkers of activation of the lymphatic drainage system of the brain during sleep and opening of the blood-brain barrier

OV Semyachkina-Glushkovskaya, AS Karavaev… - Computational and …, 2023 - Elsevier
The lymphatic drainage system of the brain (LDSB) is the removal of metabolites and wastes
from its tissues. A dysfunction of LDSB is an important sign of aging, brain oncology, the …