AGA clinical practice update on the management of refractory Helicobacter pylori infection: expert review

SC Shah, PG Iyer, SF Moss - Gastroenterology, 2021 - Elsevier
The purpose of this CPU Expert Review is to provide clinicians with guidance on the
management of Helicobacter pylori after an initial attempt at eradication therapy fails …

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

P Díaz, M Valenzuela Valderrama, J Bravo… - Frontiers in …, 2018 - frontiersin.org
Helicobacter pylori (H. pylori) infection is the major risk factor associated with the
development of gastric cancer. The transition from normal mucosa to non-atrophic gastritis …

Statins: a viable candidate for host-directed therapy against infectious diseases

SP Parihar, R Guler, F Brombacher - Nature Reviews Immunology, 2019 - nature.com
Statins were first identified over 40 years ago as lipid-lowering drugs and have been
remarkably effective in treating cardiovascular diseases. As research advanced, the …

Inducible antibacterial responses in macrophages

MJ Sweet, D Ramnath, A Singhal… - Nature Reviews …, 2024 - nature.com
Macrophages destroy bacteria and other microorganisms through phagocytosis-coupled
antimicrobial responses, such as the generation of reactive oxygen species and the delivery …

Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

Adjunctive host-directed therapy with statins improves tuberculosis-related outcomes in mice

NK Dutta, N Bruiners, MD Zimmerman… - The Journal of …, 2020 - academic.oup.com
Background Tuberculosis (TB) treatment is lengthy and complicated and patients often
develop chronic lung disease. Recent attention has focused on host-directed therapies …

Current and Future Perspectives in the Diagnosis and Management of Helicobacter pylori Infection

M Shatila, AS Thomas - Journal of Clinical Medicine, 2022 - mdpi.com
Helicobacter pylori (Hp) is a prevalent organism infecting almost half the global population. It
is a significant concern, given its associated risk of gastric cancer, which is the third leading …

Programmed cell death in Helicobacter pylori infection and related gastric cancer

Y Lin, K Liu, F Lu, C Zhai, F Cheng - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
Programmed cell death (PCD) plays a crucial role in maintaining the normal structure and
function of the digestive tract in the body. Infection with Helicobacter pylori (H. pylori) is an …

Lipids in pathophysiology and development of the membrane lipid therapy: new bioactive lipids

M Torres, S Parets, J Fernández-Díaz, R Beteta-Göbel… - Membranes, 2021 - mdpi.com
Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint
for the entry and passage of signals and other molecules. Their composition can be …

PM2.5 impairs macrophage functions to exacerbate pneumococcus-induced pulmonary pathogenesis

YW Chen, MZ Huang, CL Chen, CY Kuo… - Particle and fibre …, 2020 - Springer
Background Pneumococcus is one of the most common human airway pathogens that
causes life-threatening infections. Ambient fine particulate matter (PM) with aerodynamic …