[HTML][HTML] Towards a youth mental health paradigm: a perspective and roadmap

PJ Uhlhaas, CG Davey, UM Mehta, J Shah… - Molecular …, 2023 - nature.com
Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …

Diet and depression: exploring the biological mechanisms of action

W Marx, M Lane, M Hockey, H Aslam, M Berk… - Molecular …, 2021 - nature.com
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

Preventive psychiatry: a blueprint for improving the mental health of young people

P Fusar‐Poli, CU Correll, C Arango, M Berk… - World …, 2021 - Wiley Online Library
Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Psychiatric diagnosis and treatment in the 21st century: paradigm shifts versus incremental integration

DJ Stein, SJ Shoptaw, DV Vigo, C Lund… - World …, 2022 - Wiley Online Library
Psychiatry has always been characterized by a range of different models of and approaches
to mental disorder, which have sometimes brought progress in clinical practice, but have …

Risk and protective factors for mental disorders beyond genetics: an evidence‐based atlas

C Arango, E Dragioti, M Solmi, S Cortese… - World …, 2021 - Wiley Online Library
Decades of research have revealed numerous risk factors for mental disorders beyond
genetics, but their consistency and magnitude remain uncertain. We conducted a “meta …

[HTML][HTML] Peripheral markers of depression

A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

Oxidative stress‐related mechanisms in schizophrenia pathogenesis and new treatment perspectives

EA Ermakov, EM Dmitrieva… - Oxidative Medicine …, 2021 - Wiley Online Library
Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: a meta-analysis of …

M Solmi, MS Sharma, EF Osimo, M Fornaro… - Brain, Behavior, and …, 2021 - Elsevier
Importance It is unclear whether differences exist in the magnitude and variability of pro-
inflammatory mediators in the different phases of bipolar disorder (BD) and among subjects …

[HTML][HTML] Immune system abnormalities in schizophrenia: an integrative view and translational perspectives

EA Ermakov, MM Melamud, VN Buneva… - Frontiers in …, 2022 - frontiersin.org
The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …