Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative
damage and inflammation are pathognomonic features of Parkinson's disease (PD) and …

Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly. Contemporary treatments can only relieve symptoms but fail to delay disease …

Chronic exposure to aluminium (Al) can contribute to the progression of several neurological
and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to …

Heterocycles and their derivatives hold an important place in medicinal chemistry due to
their vast therapeutic and pharmacological significance and wider implications in drug …

The search for new drug candidates against Alzheimer's disease (AD) remains a complex
challenge for medicinal chemists due to its multifactorial pathogenesis and incompletely …

Objectives To evaluate whether the glycosylation of chrysin (CHR) enhances its protective
effects against aluminum-induced neurotoxicity. Methods To compare the antioxidant …

In the pursuit of novel antioxidant therapies for the prevention and treatment of
neurodegenerative diseases, three new arylpiperazine derivatives (LQFM181, LQFM276 …

Molecular hybridization between structural fragments from the structures of curcumin (1) and
resveratrol (2) was used as a designing tool to generate a new N-acyl-cinnamoyl-hydrazone …

Herein, it was aimed to evaluate three different extracts of the plant Asphodelus aestivus in
terms of their antioxidant capacity, total phenolic content, flavonoid profile, and …

Alzheimer's disease (AD) is a neurodegenerative disorder. Although the first case of
Alzheimer's disease was recorded over a century ago, the etiology of the disease remains …