Engineering precision nanoparticles for drug delivery
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
Targeting the RNA m6A modification for cancer immunotherapy
Abstract N 6-methyladenosine (m6A) is the most abundant epigenetic modification of RNA,
and its dysregulation drives aberrant transcription and translation programs that promote …
and its dysregulation drives aberrant transcription and translation programs that promote …
Multienzyme-like reactivity cooperatively impairs glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways in triple-negative breast cancer for sensitized …
Ferroptosis is a recently discovered route of regulated cell death that offers the opportunities
for the treatment of chemotherapy-resistant tumor indications, but its efficacy can be affected …
for the treatment of chemotherapy-resistant tumor indications, but its efficacy can be affected …
[HTML][HTML] Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle
Ferumoxytol is an intravenous iron oxide nanoparticle formulation that has been approved
by the US Food and Drug Administration (FDA) for treating anemia in patients with chronic …
by the US Food and Drug Administration (FDA) for treating anemia in patients with chronic …
Oxygen self-generating nanoreactor mediated ferroptosis activation and immunotherapy in triple-negative breast cancer
The hypoxia microenvironment of solid tumors poses a technological bottleneck for
ferroptosis and immunotherapy in clinical oncology. Nanoreactors based on special …
ferroptosis and immunotherapy in clinical oncology. Nanoreactors based on special …
Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy
Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …
macrophages holds great promise in tumor immunotherapy. As a class of professional …
[HTML][HTML] The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy
Q Yang, N Guo, Y Zhou, J Chen, Q Wei… - Acta Pharmaceutica Sinica …, 2020 - Elsevier
Macrophages have a leading position in the tumor microenvironment (TME) which paves the
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …
Superparamagnetic iron oxide nanoparticles (SPION): from fundamentals to state-of-the-art innovative applications for cancer therapy
T Vangijzegem, V Lecomte, I Ternad, L Van Leuven… - Pharmaceutics, 2023 - mdpi.com
Despite significant advances in cancer therapy over the years, its complex pathological
process still represents a major health challenge when seeking effective treatment and …
process still represents a major health challenge when seeking effective treatment and …